Evidence map›Paper›PMID 38028900›Full record

ArticleAntimicrobial stewardship & healthcare epidemiology : ASHE2023

Antibiotic stewardship in Indian palliative care: a single-center retrospective study.

David Thomas, Vijayvardhan Kamalumpundi, Amirtha Thampi, Kashelle Lockman, Mary B Carter, Navjyot Vidwan, Ann Broderick

Open access · goldAbstract read
In one paragraph

Article in Antimicrobial stewardship & healthcare epidemiology : ASHE, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

David ThomasUniversity of Louisville, School of Medicine, Louisville, KY, USA.ORCID https://orcid.org/0000-0003-1617-7647
Vijayvardhan KamalumpundiRoy J. and Lucille A. Carver College of Medicine, Iowa City, IA, USA.ORCID https://orcid.org/0000-0001-7106-7286
Amirtha ThampiPallium India, Thiruvananthapuram, Kerala, India.
Kashelle LockmanUniversity of Iowa, College of Pharmacy, Iowa City, IA, USA.ORCID https://orcid.org/0000-0001-8017-8084
Mary B CarterUniversity of Louisville, School of Medicine, Louisville, KY, USA.
Navjyot VidwanUniversity of Louisville, School of Medicine, Louisville, KY, USA.
Ann BroderickRoy J. and Lucille A. Carver College of Medicine, Iowa City, IA, USA.
University of Louisville · USIowa City VA Medical Center · USPallium India · INUniversity of Iowa · USUniversity of Minnesota · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Characterize antibiotic prescribing behaviors at an Indian palliative care center after the initiation of the Antibiotic Order Form (AOF): an antibiotic stewardship program involving a paper form to track antibiotic use and to provide prescription guidelines. Design: Retrospective chart review. Setting: Trivandrum Institute of Palliative Sciences (TIPS) is a palliative care organization in Kerala, India. Methods: Antibiotic prescription data and patient data were collected for adult patients treated at TIPS between January 1, 2017, and October 31, 2019. Descriptive statistics and a Zero-Inflated Poisson regression model were used to analyze antibiotic prescriptions. AOF completion and prescription concordance with institutional guidelines were also evaluated. Results: Out of 7,450 unique patients, 675 (9%) were prescribed 1,448 antibiotics. Age was the strongest factor in determining the number of antibiotic courses with each additional year of age decreasing the expected antibiotic prescription count by 2% per year. The most common antibiotics prescribed were topical metronidazole (44%) and penicillins (29%). Among patients who died, 5% were prescribed antibiotics within the final month of life. In total, 32% of antibiotic prescriptions were documented in AOFs, and 18% were concordant with all institutional antibiotic prescribing guidelines. Conclusions: This study is the first to analyze an antibiotic stewardship intervention in a palliative care setting within a low- and middle-income country. This retrospective study provides a benchmark of antibiotic use within Indian palliative care and highlights areas for future stewardship research including topical metronidazole use within palliative care and higher rates of antibiotic use among younger palliative care patients.

Identifiers

PMID38028900
PMCPMC10654949
OpenAlexW4388503613

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.