Evidence map›Paper›PMID 38028838›Full record

ArticleArchives of Razi Institute2023

Bac to Bac System Efficiency for Preparing HPV Type 16 Virus-Like Particle Vaccine.

H Razavi-Nikoo, E Behboudi, B Aghcheli, S M A Hashemi, A Moradi

Open access · greenAbstract read
In one paragraph

Article in Archives of Razi Institute, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

H Razavi-NikooDepartment of Microbiology, Golestan University of Medical Sciences, Gorgan, Iran.
E BehboudiDepartment of Basic Sciences, Khoy University of Medical Sciences, Khoy, Iran.
B AghcheliDepartment of Microbiology, Golestan University of Medical Sciences, Gorgan, Iran.
S M A HashemiDepartment of Microbiology, Golestan University of Medical Sciences, Gorgan, Iran.
A MoradiDepartment of Microbiology, Golestan University of Medical Sciences, Gorgan, Iran.
Golestan University of Medical Sciences · IRGolestan University · IRIslamic Azad University, Khoy Branch · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Today, the human papillomavirus (HPV) L1 protein is the main target in the construction of prophylactic HPV vaccines. The production of virus-like particles (VLPs) that closely resemble the natural structure of the HPV16 virus and induce high levels of virus-neutralizing antibodies in animals and humans is facilitated by the expression of HPV16-L1 protein in eukaryotic cells. The Bac-to-Bac system has been previously used to produce high levels of recombinant proteins. In this study, we utilized this expression system to generate HPV16-L1 VLPs in

Indexed as

Papillomavirus InfectionsVaccines, Virus-Like ParticleAnimalsBaculoviridaeHuman papillomavirus 16HumansMicroscopy, ElectronRecombinant ProteinsRecombinant ProteinsVaccines, Virus-Like ParticleBaculovirusHPVL1Protein purificationSf9Vaccine

Identifiers

PMID38028838
PMCPMC10657962
OpenAlexW4389180316

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.