Evidence map›Paper›PMID 38028753›Full record

ArticleCase reports in psychiatry2023

Progressive Neuropsychiatric Symptoms Following Recurrent COVID-19 Infections in a Previously Healthy Adolescent.

Christopher Shawl, R Hunter Clark, Matthew T Edwards, Casey Berson, Megan Zappitelli

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 68% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Christopher ShawlPrisma Health Department of Psychiatry, 701 Grove Road, Greenville, SC 29605, USA.ORCID https://orcid.org/0000-0002-2527-314X
R Hunter ClarkUniversity of South Carolina School of Medicine Greenville, 607 Grove Road, Greenville, SC 29605, USA.ORCID https://orcid.org/0000-0002-3518-1513
Matthew T EdwardsMission Health Hospital, HCA Healthcare, 428 Biltmore Avenue, Asheville, NC 28801, USA.ORCID https://orcid.org/0009-0006-0361-187X
Casey BersonPrisma Health Department of Psychiatry, 701 Grove Road, Greenville, SC 29605, USA.ORCID https://orcid.org/0000-0002-0373-5809
Megan ZappitelliPrisma Health Department of Psychiatry, 701 Grove Road, Greenville, SC 29605, USA.ORCID https://orcid.org/0000-0002-1905-0783
Prisma Health · USMission Health · USUniversity of South Carolina · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This is the almost 2-year-long course of a 16-year-old male without significant psychiatry history who abruptly developed symptoms of obsessive-compulsive disorder (OCD) and psychosis following a confirmed coronavirus disease 2019 (COVID-19) infection. His symptoms worsened following a confirmed reinfection with COVID-19. He responded poorly to treatment with selective serotonin reuptake inhibitors, antipsychotics, and benzodiazepines. This case highlights an emerging phenomenon of post-COVID-19 neuropsychiatric sequelae and presents a complicated diagnostic and treatment challenge. The differential for this patient was explored and outlined in detail, and the medical workup recommendations for new-onset mental status changes were reviewed as they pertain to the patient's assessment and treatment course. While there are several case reports of adolescents with abrupt-onset OCD and psychosis symptoms following COVID-19 infections, none of these reports include worsening of symptoms following reinfection, and few reports follow patients beyond initial hospitalization and treatment.

Identifiers

PMID38028753
PMCPMC10651327
OpenAlexW4388488919

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.