Evidence map›Paper›PMID 38028644›Full record

ReviewJournal of intensive medicine2023

The intensity of organ support: Restrictive or aggressive therapy for critically ill patients.

Hongxiang Li, Yuting Li, Yao Fu, Xinyu Zhang, Dong Zhang

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of intensive medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hongxiang LiDepartment of Intensive Care Medicine, The First Hospital of Jilin University, Changchun 130021, Jilin, China.
Yuting LiDepartment of Intensive Care Medicine, The First Hospital of Jilin University, Changchun 130021, Jilin, China.
Yao FuDepartment of Intensive Care Medicine, The First Hospital of Jilin University, Changchun 130021, Jilin, China.
Xinyu ZhangDepartment of Intensive Care Medicine, The First Hospital of Jilin University, Changchun 130021, Jilin, China.
Dong ZhangDepartment of Intensive Care Medicine, The First Hospital of Jilin University, Changchun 130021, Jilin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The intensity of organ support has received attention in recent years. To make better clinical decisions, we should understand the mechanisms and benefits, and disadvantages of the different intensities of organ support in critically ill patients. Therapeutic strategies such as supplemental oxygen therapy, mechanical ventilation, respiratory stimulant, vasoactive agents, transfusion, albumin infusion, fluid management, renal placement, and nutrition support, if they are implemented in accordance with an aggressive strategy, could result in side effects and/or complications, resulting in iatrogenic harm in critically ill patients. It is found that the intensity of organ support is not a determining factor in prognosis. A normal rather than supernormal physiological target is recommended for support therapy.

Indexed as

Aggressive therapyCritically ill patientsOrgan supportPrognosisRestrictive therapy

Identifiers

PMID38028644
PMCPMC10658039

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.