ArticleJournal of intensive medicine2023
Prevention of ventilator-associated pneumonia through care bundles: A systematic review and meta-analysis.
Article in Journal of intensive medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.
- Effect of acute kidney injury care bundle on kidney outcomes in cardiac patients receiving critical care: a systematic review and meta-analysis.BMC nephrology · 2025Pooled it
- A National Collaborative Project to Decrease Healthcare-Associated Infections in Intensive Care Units: Results from Stop Hospital Infection, in Portugal.Antibiotics (Basel, Switzerland) · 2026Article
- Association between preoperative blood glucose levels and postoperative pneumonia in neurosurgical patients: a retrospective study.Journal of thoracic disease · 2026Article
- The Start of a Good Innings, 50 Years of Intensive Care Medicine.World journal of surgery · 2026Review
- Article
- Incidence, Mortality, and Determinants of Ventilator-Associated Pneumonia Among Pediatric Patients at the National Referral Hospital, Bhutan: A Prospective Cohort Study.Health science reports · 2026Article
- Ventilator-Associated Pneumonia (VAP) Prevention Bundle: A Multicenter Cross-Sectional Saudi Study to Assess Knowledge, Adherence, and Perceived Barriers Among ICU Practitioners in Hail Region.Pathogens (Basel, Switzerland) · 2026Article
- Antimicrobial Peptides in Preventive Medicine: Current Perspectives on Coating Strategies.ACS infectious diseases · 2026Review
- A potential bundle for preventing ventilator-associated pneumonia in the emergency department: A narrative review.The Journal of international medical research · 2026Article
- Impact of Plan-Do-Study-Act Cycle-Based Quality Improvement on Head-of-Bed Elevation Compliance, Cuff Pressure Management and Ventilator-Associated Pneumonia in Intensive Care Units: A Before-After Study.Journal of multidisciplinary healthcare · 2026Article
- Interpreting QI Outcomes in Neonatal Infection Control.Indian pediatrics · 2026Article
- Evaluation of the effectiveness of a multimodal aspiration prevention system in stroke rehabilitation nursing.PloS one · 2026Article
- Article
- Sustained effect of a multifaceted VAP prevention program over more than seven years including the COVID-19 pandemic.Antimicrobial resistance and infection control · 2025Article
- Article
- Intensive and critical care nurses' compliance, barriers, and challenges with ventilator-associated pneumonia prevention: a cross-sectional study.BMC nursing · 2025Article
- A multimedia tool for infection prevention and control practices in the intensive care unit: a participatory interventional before-after study.Infection prevention in practice · 2025Article
- The Development of a 10-Item Ventilator-Associated Pneumonia Care Bundle in the General Intensive Care Unit of a Tertiary Hospital in Vietnam: Lessons Learned.Healthcare (Basel, Switzerland) · 2025Review
- Effect of humidification intervention combined with cluster nursing on ventilator-associated pneumonia in ICU patients.Frontiers in public health · 2025Observational
- Hospital Context Determinants of Variability in Healthcare-Associated Infection Prevalence: Multi-Level Analysis.Microorganisms · 2024Article
Corrections and comments
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Authors and funding
10 authors at 6 institutions in 8 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Ventilator-associated pneumonia (VAP) represents a common hospital-acquired infection among mechanically ventilated patients. We summarized evidence concerning ventilator care bundles to prevent VAP. Methods: A systematic review and meta-analysis were performed. Randomized controlled trials and controlled observational studies of adults undergoing mechanical ventilation (MV) for at least 48 h were considered for inclusion. Outcomes of interest were the number of VAP episodes, duration of MV, hospital and intensive care unit (ICU) length of stay, and mortality. A systematic search was conducted in the MEDLINE, the Cochrane Library, and the Web of Science between 1985 and 2022. Results are reported as odds ratio (OR) or mean difference (MD) with 95% confidence intervals (CI). The PROSPERO registration number is CRD42022341780. Results: Thirty-six studies including 116,873 MV participants met the inclusion criteria. A total of 84,031 participants underwent care bundles for VAP prevention. The most reported component of the ventilator bundle was head-of-bed elevation ( Conclusions: The implementation of ventilator care bundles reduced the number of VAP episodes and the duration of MV in adult ICUs. Their application in combination with educational activities seemed to improve clinical outcomes.
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