Evidence map›Paper›PMID 38028583›Full record

ArticleFrontiers in genetics2023

Expression of acetylated histones H3 and H4 and histone deacetylase enzymes HDAC1, HDAC2 and HDAC6 in simple mammary carcinomas of female dogs.

Igor Luiz Salardani Senhorello, Oscar Rodrigo Sierra Matiz, Isabela Cristina Canavari, Giovanny Vargas Hernandez, Letícia Abrahão Anai, Roberto Andrés Navarrete Ampuero, Josiane Moraes Pazzini, Cibele Maria Prado, Flavio Vieira Meirelles, Rosemeri de Oliveira Vasconcelos and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in genetics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. The role of epigenetic alterations in canine mammary cancer.The Journal of reproduction and development · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Igor Luiz Salardani SenhorelloDepartment of Veterinary Clinic and Surgery, Faculty of Agricultural and Veterinary Sciences, Universidade Estadual Paulista, Jaboticabal, SP, Brazil.
Oscar Rodrigo Sierra MatizDepartment of Veterinary Clinic and Surgery, Faculty of Agricultural and Veterinary Sciences, Universidade Estadual Paulista, Jaboticabal, SP, Brazil.
Isabela Cristina CanavariDepartment of Veterinary Clinic and Surgery, Faculty of Agricultural and Veterinary Sciences, Universidade Estadual Paulista, Jaboticabal, SP, Brazil.
Giovanny Vargas HernandezDepartment of Animal Health, Universidad Nacional de Colombia, Bogotá, Colombia.
Letícia Abrahão AnaiAutonomous Veterinarian, São Paulo, Brazil.
Roberto Andrés Navarrete AmpueroAutonomous Veterinarian, São Paulo, Brazil.
Josiane Moraes PazziniAutonomous Veterinarian, São Paulo, Brazil.
Cibele Maria PradoDepartment of Veterinary Medicine, Faculty of Animal Science and Food Engineering, Universidade de São Paulo-USP, Pirassununga, São Paulo, Brazil.
Flavio Vieira MeirellesDepartment of Veterinary Medicine, Faculty of Animal Science and Food Engineering, Universidade de São Paulo-USP, Pirassununga, São Paulo, Brazil.
Rosemeri de Oliveira VasconcelosDepartment of Veterinary Clinic and Surgery, Faculty of Agricultural and Veterinary Sciences, Universidade Estadual Paulista, Jaboticabal, SP, Brazil.
E Mirela Tinucci-CostaDepartment of Veterinary Clinic and Surgery, Faculty of Agricultural and Veterinary Sciences, Universidade Estadual Paulista, Jaboticabal, SP, Brazil.
Universidade Estadual Paulista (Unesp) · BRAssociação Brasileira de Oncologia Veterinária · BRUniversidade de São Paulo · BRUniversidad Nacional de Colombia · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Histone deacetylation is an important mechanism involved in human breast cancer tumorigenesis and recent veterinary oncology studies also demonstrate a similar relationship in some canine neoplasms. The use of HDAC inhibitors

Indexed as

dogsepigenetichistonesmammary carcinomasprognosis

Identifiers

PMID38028583
PMCPMC10666162
OpenAlexW4388636179

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.