Evidence map›Paper›PMID 38028521›Full record

ArticleInternational journal of ophthalmology2023

Retinal thickness and fundus blood flow density changes in chest pain subjects with dyslipidemia.

Jin Wang, Yu-Cen Wang, Pei Zhang, Xin Wang, Rong-Rong Zong, Jing Jiang, Yu Zhang, Yi-Wen Qian, Qing-Jian Li, Zhi-Liang Wang

Open access · goldAbstract read
In one paragraph

Article in International journal of ophthalmology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Association of Remnant Cholesterol With the Retinal Capillary Plexus.Translational vision science & technology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Jin WangDepartment of Cardiology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200010, China.
Yu-Cen WangDepartment of Ophthalmology, Huashan Hospital, Fudan University, Shanghai 200040, China.
Pei ZhangDepartment of Ophthalmology, Huashan Hospital, Fudan University, Shanghai 200040, China.
Xin WangDepartment of Ophthalmology, Huashan Hospital, Fudan University, Shanghai 200040, China.
Rong-Rong ZongFujian Provincial Key Laboratory of Ophthalmology and Visual Science; Fujian Engineering and Research Center of Eye Regenerative Medicine; Eye Institute of Xiamen University; Xiamen University School of Medicine, Xiamen 361005, Fujian Province, China.
Jing JiangDepartment of Ophthalmology, Huashan Hospital, Fudan University, Shanghai 200040, China.
Yu ZhangDepartment of Ophthalmology, Huashan Hospital, Fudan University, Shanghai 200040, China.
Yi-Wen QianDepartment of Ophthalmology, Huashan Hospital, Fudan University, Shanghai 200040, China.
Qing-Jian LiDepartment of Ophthalmology, Huashan Hospital, Fudan University, Shanghai 200040, China.
Zhi-Liang WangDepartment of Ophthalmology, Huashan Hospital, Fudan University, Shanghai 200040, China.
Fudan University · CNSecond Military Medical University · CNXiamen University · CNShanghai Ninth People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo assess the retinal thickness and fundus blood flow density changes in chest pain patients with dyslipidemia using optical coherence tomography angiography (OCTA).

methodsAll subjects with chest pain as the main symptom accepted a comprehensive ophthalmological examination. According to the serum lipid levels, the participants were divided into the control group and the dyslipidemia group. The retina thickness and fundus blood flow density were determined using OCTA.

resultsThe study enrolled 87 left eyes from 87 adults with dyslipidemia and 87 left eyes from age- and sex-matched participants without dyslipidemia. The retina of dyslipidemia subjects was significantly thinner than that of the controls in the inferior (

conclusionDyslipidemia may contribute to the decrease in retinal thickness and fundus blood flow density. Further validation of the association between abnormal lipid metabolism and fundus microcirculation alterations needs to be carried out in chest pain patients.

Indexed as

blood flow densitydyslipidemiaoptical coherence tomography angiographyretinal thicknessserum lipid

Identifiers

PMID38028521
PMCPMC10626367
OpenAlexW4387945223

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.