ArticleFrontiers in cardiovascular medicine2023
Identification of risk factors for hypertension in overweight and obese people and analysis of risk factor interactions: an R-based analysis.
Article in Frontiers in cardiovascular medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed, 4 citations in OpenAlex.
- Global diet quality score and risk of hypertension in Iranian adults: Tehran lipid and glucose study.Public health nutrition · 2025Article
- Development and validation of a nomogram model for predicting the risk of MAFLD in the young population.Scientific reports · 2024Article
- Investigating the Prevalence and Predictors of Uncontrolled Hypertension: A Cross-Sectional Study in Gujarat, India.Cureus · 2024Article
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3 authors at 3 institutions in 1 country.
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Abstract
Objective: This study identified the independent risk factors for hypertension in overweight and obese people and also analyzed the interaction between the risk factors. Methods: A total of 5,098 overweight and obese people were enrolled in this study. First, the clinical metabolic characteristics of hypertension and control groups were compared. The logistic regression (LR) and classification and regression trees (CRT)-based decision tree (DT) models were used to screen the independent risk factors for hypertension in overweight and obese people. The multiplicative and additive scale analyses were used to analyze the two risk factors with interaction from the perspective of statistics and biological interaction. Finally, the receiver operating characteristic (ROC) and calibration curves were used to analyze the accuracy and identification ability of the LR and DT models. Results: Age, UA, FPG, SBP, Cr, AST, TG, and FPG were higher in the hypertension group than in the control group ( Conclusion: The independent risk factors for hypertension in overweight and obese people included NAFLD, FPG, age, TG, LDL-c, UA, and Cr. Among these, age + UA exhibited synergistic interaction, thereby providing a reference for the prevention and control of hypertension in overweight and obese people.
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