Evidence map›Paper›PMID 38028338›Full record

ArticleJournal of clinical and translational science2023

REAP-2: An interactive quantitative tool for robust and efficient dose-response curve estimation.

Xinying Fang, Xinyi Liu, Vernon M Chinchilli, Michael Wang, Hong-Gang Wang, Nikolay V Dokholyan, Chan Shen, J Jack Lee, Shouhao Zhou

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical and translational science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xinying FangDepartment of Public Health Sciences, Pennsylvania State University, Hershey, PA, USA.ORCID https://orcid.org/0000-0001-9121-5717
Xinyi LiuDepartment of Public Health Sciences, Pennsylvania State University, Hershey, PA, USA.
Vernon M ChinchilliDepartment of Public Health Sciences, Pennsylvania State University, Hershey, PA, USA.
Michael WangDepartment of Lymphoma and Myeloma, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Hong-Gang WangDepartment of Pharmacology, Pennsylvania State University, Hershey, PA, USA.
Nikolay V DokholyanDepartment of Pharmacology, Pennsylvania State University, Hershey, PA, USA.
Chan ShenDepartment of Public Health Sciences, Pennsylvania State University, Hershey, PA, USA.
J Jack LeeDepartment of Biostatistics, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Shouhao ZhouDepartment of Public Health Sciences, Pennsylvania State University, Hershey, PA, USA.ORCID https://orcid.org/0000-0002-8124-5047

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

REAP-2 is an interactive dose-response curve estimation tool for Robust and Efficient Assessment of drug Potency. It provides user-friendly dose-response curve estimation for

Indexed as

cancer biologydose-response estimationdrug potencyED50IC50median-effect equationquantitative toolrobust beta regressionShinysigmoid functionsoftware

Identifiers

PMID38028338
PMCPMC10643933

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.