Evidence map›Paper›PMID 38028198›Full record

ArticleMolecular therapy. Nucleic acids2023

ASO-mediated knockdown or kinase inhibition of

Rebecca L Wallings, Julian R Mark, Hannah A Staley, Drew A Gillett, Noelle Neighbarger, Holly Kordasiewicz, Warren D Hirst, Malú Gámez Tansey

Open access · goldAbstract read
In one paragraph

Article in Molecular therapy. Nucleic acids, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Parkinson's-Linked LRRK2 and GBA1 Mutations Modulate the Peripheral Immune Response to Pseudomonas aeruginosa.Movement disorders : official journal of the Movement Disorder Society · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Rebecca L WallingsDepartment of Neuroscience, University of Florida, College of Medicine, McKnight Brain Institute, Gainesville, FL 32610, USA.
Julian R MarkDepartment of Neuroscience, University of Florida, College of Medicine, McKnight Brain Institute, Gainesville, FL 32610, USA.
Hannah A StaleyDepartment of Neuroscience, University of Florida, College of Medicine, McKnight Brain Institute, Gainesville, FL 32610, USA.
Drew A GillettDepartment of Neuroscience, University of Florida, College of Medicine, McKnight Brain Institute, Gainesville, FL 32610, USA.
Noelle NeighbargerDepartment of Neuroscience, University of Florida, College of Medicine, McKnight Brain Institute, Gainesville, FL 32610, USA.
Holly KordasiewiczNeurology, Ionis Pharmaceuticals, 2855 Gazelle Court, Carlsbad, CA 92010, USA.
Warren D HirstNeurodegenerative Diseases Research Unit, Biogen, 115 Broadway, Cambridge, MA 02142, USA.
Malú Gámez TanseyDepartment of Neuroscience, University of Florida, College of Medicine, McKnight Brain Institute, Gainesville, FL 32610, USA.
University of Florida · USBiogen (United States) · USIonis Pharmaceuticals (United States) · USUniversity of Florida Health · US

Funding

Role of central and peripheral immune crosstalk in FTD-Grn neurodegenerationRF1NS128800 · NINDS · UNIVERSITY OF FLORIDA · PI FINKBEINER, STEVEN M, TANSEY, MARIA DE LOURDES GAMEZ · 2022 to 2022
$2.4M
Role of Gut Inflammation and Immunity on Proteostasis, Noradrenergic Degeneration and AD riskRF1AG057247 · NIA · UNIVERSITY OF FLORIDA · PI NEISH, ANDREW S, TANSEY, MARIA DE LOURDES GAMEZ · 2017 to 2017
$1.6M
NIA NIH HHS RF1 AG057247NINDS NIH HHS RF1 NS128800
6 · The paper itself

Abstract

Genetic variation around the

Indexed as

antigen presentationantisense oligonucleotideimmune responseLRRK2lysosomal tubulesMT: Oligonucleotides: Therapies and Applications

Identifiers

PMID38028198
PMCPMC10661462
OpenAlexW4387816591

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.