Evidence map›Paper›PMID 38027965›Full record

ArticleHeliyon2023

The Wood equation allows consistent fitting of individual antibody-response profiles of Zika virus or SARS-CoV-2 infected patients.

J Denis, A Garnier, D Claverie, F De Laval, S Attoumani, B Tenebray, G A Durand, B Coutard, I Leparc-Goffart, J N Tournier and 2 more

Open access · goldAbstract read
In one paragraph

Article in Heliyon, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

J DenisUnité Interaction Hôte - Pathogene, Institut de Recherche Biomédicale des Armées, Brétigny-sur-Orge, France.
A GarnierUnité Interaction Hôte - Pathogene, Institut de Recherche Biomédicale des Armées, Brétigny-sur-Orge, France.
D ClaverieUnité de Neurophysiologie du Stress, Institut de Recherche Biomédicale des Armées, 1 place du Général Valérie André BP73, Brétigny-sur-Orge Cedex, France.
F De LavalService de Santé des Armées, Centre d'Epidémiologie et de Santé Public des Armées, Marseille, France.
S AttoumaniUnité des Virus Émergents (UVE: Aix-Marseille Univ - IRD 190 - Inserm 1207 - IHU Méditerranée Infection), Marseille, France.
B TenebrayCentre National de Référence des Arbovirus, Institut de Recherche Biomédicale des Armées, Marseille, France.
G A DurandCentre National de Référence des Arbovirus, Institut de Recherche Biomédicale des Armées, Marseille, France.
B CoutardUnité des Virus Émergents (UVE: Aix-Marseille Univ - IRD 190 - Inserm 1207 - IHU Méditerranée Infection), Marseille, France.
I Leparc-GoffartCentre National de Référence des Arbovirus, Institut de Recherche Biomédicale des Armées, Marseille, France.
J N TournierUnité Interaction Hôte - Pathogene, Institut de Recherche Biomédicale des Armées, Brétigny-sur-Orge, France.
S BriolantUnité de Parasitologie et Entomologie, Département de Microbiologie et des Maladies Infectieuses, Institut de Recherche Biomédicale des Armées, Marseille, France.
C BadautUnité des Virus Émergents (UVE: Aix-Marseille Univ - IRD 190 - Inserm 1207 - IHU Méditerranée Infection), Marseille, France.
Inserm · FRInstitut de Médecine Tropicale du Service de Santé des Armées · FRAix-Marseille Université · FRInstitut Pasteur · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antibody kinetic curves obtained during a viral infection are often fitted using aggregated patient data, hiding the heterogeneity of individual humoral immune responses. Individual antibody responses can be modeled using the Wood equation and grouped according to their profile. Such modeling takes into account several important kinetic parameters, such as the day when antibody detection becomes positive [daypos], the day of the maximal response [daymax], the maximum antibody level [levelmax], and the day when antibody detection becomes negative [dayneg]. Potential associations between these profiles and studied factors can then be tested.

Indexed as

Curve fitHumoral immune responseKineticSARS-CoV-2Wood equationZika virus

Identifiers

PMID38027965
PMCPMC10658335
OpenAlexW4388461339

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.