ArticleHeliyon2023
One-pot synthesized copper-imidazole-2-carboxaldehyde complex material with oxidase-like activity for the colorimetric detection of glutathione and ascorbic acid.
Article in Heliyon, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 12 citations in OpenAlex.
- Advancements in Bimetallic Metal-Organic Frameworks for Oral Medicine.International dental journal · 2026Review
- Article
- Nanolevel of detection of ascorbic acid using horse-radish peroxidase inhibition assay.Heliyon · 2024Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Due to the copper (Cu) active sites, its complexes with oxidase-like activity have superior catalytic properties, which can catalyze a series of specific substrates like 3,3',5,5'-tetramethylbenzidine (TMB), producing colorimetric reactions for the detection of different reducing small-molecule compounds. Attribute to the competitive coordination effects between water molecules and central Cu ions, most of the Cu complexes can hardly be used in the pure aqueous reaction system. In this study, a Cu-based material (Cu-imidazole-2-carboxaldehyde, Cu-ICA) was prepared using copper ions and ICA through a one-step process in the water solution. After the morphology of the material being characterized, the mimetic enzyme behavior of the Cu-ICA was demonstrated through the TMB oxidation. Compared to the other reported oxidase-like mimics, Cu-ICA has better aqueous stability and oxidase-like activity, and shows a higher
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