Evidence map›Paper›PMID 38027487›Full record

ArticleFrontiers in neuroscience2023

Electroacupuncture at HT5 + GB20 promotes brain remodeling and significantly improves swallowing function in patients with stroke.

Xuefeng Fu, Hao Li, Wen Yang, Xuezheng Li, Lijun Lu, Hua Guo, Kaifeng Guo, Zhen Huang

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06737549 (Effect of Specific Mode Electroacupuncture Stimulation Combined with NGF on Dysphagia After Ischaemic Stroke), which is not on this map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06737549 phase4recruitingnot on this mapstarted 2024, after this paper: background citation

Effect of Specific Mode Electroacupuncture Stimulation Combined with NGF on Dysphagia After Ischaemic Stroke: a Pilot Randomized Controlled Trial

TypeinterventionalSponsorThe Third Affiliated hospital of Zhejiang Chinese Medical UniversityRan2024 to 2027Enrolled144ConditionsIschemic Stroke, DysphagiaArmsNerver growth factor (NGF) injection, Placebo injection, EA intervention, Acupuncture intervention
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 10 citations in OpenAlex.

  1. Pooled it
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  3. Trial
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  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Xuefeng FuGuangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Hao LiGuangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Wen YangGuangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Xuezheng LiGuangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Lijun LuGuangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Hua GuoDepartment of Rehabilitation Medicine, Guangzhou Panyu Central Hospital, Guangzhou, Guangdong, China.
Kaifeng GuoDepartment of Rehabilitation Medicine, Guangzhou Panyu Central Hospital, Guangzhou, Guangdong, China.
Zhen HuangGuangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Guangzhou University of Chinese Medicine · CNPanyu District Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: This study compared the differences in the degree of brain activation, and swallowing function scales in patients with post-stroke dysphagia after treatment. We explored the mechanism of cortical remodeling and the improvement effect of electroacupuncture on swallowing function in patients and provided a theoretical basis for the clinical application of electroacupuncture. Methods: Fifty patients with post-stroke dysphagia were randomized to the control or electroacupuncture group. The control group underwent conventional swallowing rehabilitation for 30 min each time for 12 sessions. In the electroacupuncture group, electroacupuncture was performed based on conventional swallowing rehabilitation for 30 min each time for 12 sessions. Cortical activation tests and swallowing function assessments were performed before and after treatment. Statistical analyses were used to investigate the differences within and between the two groups to explore the treatment effects. Results: There were no statistical differences in clinical characteristics and baseline data between the two groups before treatment. Cortical activation and swallowing function were improved to different degrees in both groups after treatment compared with before treatment. After treatment, the electroacupuncture group showed higher LPM ( Conclusion: This study demonstrated that electroacupuncture based on conventional treatment activated more of the cerebral cortex associated with swallowing and promoted functional connectivity and remodeling of the brain. Accompanying the brain remodeling, patients in the electroacupuncture group also showed greater improvement in swallowing function. Clinical trial registration: ClinicalTrials.gov, ChiCTR2300067457.

Indexed as

electroacupunctureGB20HT5near-infrared spectroscopy techniqueswallowing

Identifiers

PMID38027487
PMCPMC10656700
OpenAlexW4388225650

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.