Evidence map›Paper›PMID 38027472›Full record

ArticleFrontiers in neuroscience2023

Applicability of clinical genetic testing for deep brain stimulation treatment in monogenic Parkinson's disease and monogenic dystonia: a multidisciplinary team perspective.

Valentino Rački, Mario Hero, Eliša Papić, Gloria Rožmarić, Nada Starčević Čizmarević, Darko Chudy, Borut Peterlin, Vladimira Vuletić

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Observational
  2. Article
  3. Clinical Utility ofGenes · 2026
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Valentino Rački *Department of Neurology, Clinical Hospital Center Rijeka, Rijeka, Croatia.
Mario Hero *Department of Neurology, Clinical Hospital Center Rijeka, Rijeka, Croatia.
Eliša PapićDepartment of Neurology, Clinical Hospital Center Rijeka, Rijeka, Croatia.
Gloria RožmarićDepartment of Neurology, Clinical Hospital Center Rijeka, Rijeka, Croatia.
Nada Starčević ČizmarevićDepartment of Medical Genomics and Biology, Faculty of Medicine, University of Rijeka, Rijeka, Croatia.
Darko ChudyDepartment of Neurosurgery, Clinical Hospital Dubrava, Zagreb, Croatia.
Borut PeterlinClinical Institute of Genomic Medicine, University Medical Centre Ljubljana, Ljubljana, Slovenia.
Vladimira VuletićDepartment of Neurology, Clinical Hospital Center Rijeka, Rijeka, Croatia.
University of Rijeka · HRLjubljana University Medical Centre · SIUniversity Hospital Dubrava · HR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this perspective article, we highlight the possible applicability of genetic testing in Parkinson's disease and dystonia patients treated with deep brain stimulation (DBS). DBS, a neuromodulatory technique employing electrical stimulation, has historically targeted motor symptoms in advanced PD and dystonia, yet its precise mechanisms remain elusive. Genetic insights have emerged as potential determinants of DBS efficacy. Known PD genes such as

Indexed as

deep brain stimulationdystoniagenetic testingParkinson’s diseasewhole-exome sequencing

Identifiers

PMID38027472
PMCPMC10667448
OpenAlexW4388633197

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.