Evidence map›Paper›PMID 38027309›Full record

ArticleFrontiers in pediatrics2023

Results and complications of bilateral limb lengthening in achondroplasia: a retrospective analysis.

Fabio Verdoni, Riccardo Giorgino, Camilla Virgilio, Alessandra Nannini, Marco Viganò, Domenico Curci, Giuseppe Michele Peretti, Laura Mangiavini

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Fabio VerdoniIRCCS Istituto Ortopedico Galeazzi, Milan, Italy.
Riccardo GiorginoIRCCS Istituto Ortopedico Galeazzi, Milan, Italy.
Camilla VirgilioFaculty of Medicine and Surgery, University of Milan, Milan, Italy.
Alessandra NanniniIRCCS Istituto Ortopedico Galeazzi, Milan, Italy.
Marco ViganòIRCCS Istituto Ortopedico Galeazzi, Milan, Italy.
Domenico CurciIRCCS Istituto Ortopedico Galeazzi, Milan, Italy.
Giuseppe Michele PerettiIRCCS Istituto Ortopedico Galeazzi, Milan, Italy.
Laura MangiaviniIRCCS Istituto Ortopedico Galeazzi, Milan, Italy.
Istituto Ortopedico Galeazzi · ITUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Achondroplasia is one of the main causes of disharmonic dwarfism. Patients with achondroplasia might have physical and psychological limitations due to their disproportionate stature. Surgical limb lengthening is the only practical option available to achieve a stature comparable to normal population range. The purpose of this study is to analyze results and complications of our lengthening protocol. Methods: A retrospective analysis was performed on 33 patients with achondroplasia (21 females and 12 males) undergoing simultaneous bilateral tibia or femur lengthening in four surgical stages from 2017 to 2021 (46 lengthening procedures, with a total of 56 tibias and 36 femurs). For each patient, patients' characteristics and antero-posterior and lateral radiographs were obtained. The following parameters were analyzed: duration of lengthening with external fixator, amount of lengthening, complications or events that influenced outcomes and the healing index (HI). Results: The average tibial and femoral gain was 7.9 cm and 6.9 cm, respectively. The tibiae achieved better results than the femurs ( Conclusions: Bilateral parallel lower limb lengthening in four surgical steps may be a viable technique in patients with achondroplasia.

Indexed as

achondroplasiacomplicationsexternal fixationfemurlimb lengtheningoutcomestibia

Identifiers

PMID38027309
PMCPMC10655023
OpenAlexW4388303593

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.