Evidence map›Paper›PMID 38027217›Full record

Observational studyFrontiers in endocrinology2023

Renal complications in chronic hypoparathyroidism - a systematic cross-sectional assessment.

Karen Gronemeyer, Carmina Teresa Fuss, Franca Hermes, Armin Plass, Ann-Cathrin Koschker, Anke Hannemann, Henry Völzke, Stefanie Hahner

Registry-linked trialOpen access · goldAbstract readObservational Study
In one paragraph

Observational study in Frontiers in endocrinology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05585593 (Registry and Biobank for Patients With Hypoparathyroidism Wuerzburg), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05585593 recruitingnot on this map

Registry and Biobank for Patients With Hypoparathyroidism Wuerzburg

TypeobservationalSponsorUniversity of WuerzburgRan2017 to 2032Enrolled300ConditionsComorbidities and Coexisting Conditions, Morality, Hypocalcemia, Hypercalcemia
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
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  4. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Karen Gronemeyer *Department of Medicine I, Division of Endocrinology and Diabetes, University Hospital, University of Wuerzburg, Wuerzburg, Germany.
Carmina Teresa Fuss *Department of Medicine I, Division of Endocrinology and Diabetes, University Hospital, University of Wuerzburg, Wuerzburg, Germany.
Franca HermesDepartment of Medicine I, Division of Endocrinology and Diabetes, University Hospital, University of Wuerzburg, Wuerzburg, Germany.
Armin PlassDepartment of Medicine I, Division of Endocrinology and Diabetes, University Hospital, University of Wuerzburg, Wuerzburg, Germany.
Ann-Cathrin KoschkerDepartment of Medicine I, Division of Endocrinology and Diabetes, University Hospital, University of Wuerzburg, Wuerzburg, Germany.
Anke HannemannInstitute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany.
Henry VölzkeGerman Centre for Cardiovascular Research, Partner Site Greifswald, Greifswald, Germany.
Stefanie HahnerDepartment of Medicine I, Division of Endocrinology and Diabetes, University Hospital, University of Wuerzburg, Wuerzburg, Germany.
German Centre for Cardiovascular Research · DEUniversitätsmedizin Greifswald · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Context: Although renal long-term complications are acknowledged in chronic hypoparathyroidism (HPT), standardized investigations are scarce. Objective: To systematically investigate renal complications and their predictors in hypoparathyroid patients compared to matched individuals. Design: Prospective observational study in 161 patients with chronic HPT. Methods: Patients received renal ultrasound, clinical and laboratory assessments. An individual 1:3 matching with participants from the German population-based Study of Health in Pomerania was performed. Results: Of 161 patients (92% postoperative HPT), prevalence of eGFR <60ml/min/1.73m Conclusions: Prevalence of impaired renal function among patients with chronic HPT is increased and independent from visible renal calcifications. Depending on exclusion of patients with rhPTH therapy, regression analysis revealed disease duration and serum phosphate or disease duration and 24-hour urinary calcium excretion as predictors for renal calcifications. Clin Trials Identifier: NCT05585593.

Indexed as

CalcinosisHypoparathyroidismNephrocalcinosisCalciumCross-Sectional StudiesHumansKidneyPhosphatesCalciumPhosphatesHypoparathyroidismParathyreoidectomyrenal calcificationRenal Insufficiencyultrasound

Identifiers

PMID38027217
PMCPMC10654620
OpenAlexW4388298261

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.