Evidence map›Paper›PMID 38027024›Full record

ArticleFrontiers in pharmacology2023

Discovery of inhibitors of protein tyrosine phosphatase 1B contained in a natural products library from Mexican medicinal plants and fungi using a combination of enzymatic and

Miriam Díaz-Rojas, Martin González-Andrade, Rodrigo Aguayo-Ortiz, Rogelio Rodríguez-Sotres, Araceli Pérez-Vásquez, Abraham Madariaga-Mazón, Rachel Mata

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Miriam Díaz-RojasFacultad de Química, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Martin González-AndradeFacultad de Medicina, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Rodrigo Aguayo-OrtizFacultad de Química, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Rogelio Rodríguez-SotresFacultad de Química, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Araceli Pérez-VásquezFacultad de Química, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Abraham Madariaga-MazónInstituto de Química Unidad Mérida and Instituto de Investigaciones en Matemáticas Aplicadas y en Sistemas Unidad Mérida, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Rachel MataFacultad de Química, Universidad Nacional Autónoma de México, Mexico City, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This work aimed to discover protein tyrosine phosphatase 1B (PTP1B) inhibitors from a small molecule library of natural products (NPs) derived from selected Mexican medicinal plants and fungi to find new hits for developing antidiabetic drugs. The products showing similar IC

Indexed as

canophyllolchemical spaceE/Z vermelhotinPTP1Bscaffold hops

Identifiers

PMID38027024
PMCPMC10644722

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.