Evidence map›Paper›PMID 38026967›Full record

ArticleFrontiers in pharmacology2023

Apoptosis mechanisms induced by 15d-PMJ

Hussam Albassam, Daniel A Ladin, Ahmed Elhassanny, Colin Burns, Rukiyah Van Dross-Anderson

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 68% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Hussam AlbassamDepartment of Pharmacology and Toxicology, Brody School of Medicine, East Carolina University, Greenville, NC, United States.
Daniel A LadinDepartment of Pharmacology and Toxicology, Brody School of Medicine, East Carolina University, Greenville, NC, United States.
Ahmed ElhassannyDepartment of Pharmacology and Toxicology, Brody School of Medicine, East Carolina University, Greenville, NC, United States.
Colin BurnsDepartment of Chemistry, East Carolina University, Greenville, NC, United States.
Rukiyah Van Dross-AndersonDepartment of Pharmacology and Toxicology, Brody School of Medicine, East Carolina University, Greenville, NC, United States.
East Carolina University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Agents that stimulate the endoplasmic reticulum (ER) stress pathway are being exploited pharmacologically to induce cancer cell death. Cytotoxic ER stress is typically regulated by the transcription factor, C/EBP homologous protein 10 (CHOP10). Products of CHOP10 transcription include the pro-apoptotic proteins: ER oxidoreductase 1α (ERO1α), death receptor-5 (DR5), and tribbles-related protein 3 (TRB3). Our previous findings showed cell death induced by 15-deoxy- Δ12,14 prostamide J

Indexed as

AktapoptosiscancerCHOP10drug developmentendoplasmic reticulum stressprostaglandin J2TRB3

Identifiers

PMID38026967
PMCPMC10652392
OpenAlexW4388232511

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.