ReviewFrontiers in bioengineering and biotechnology2023
Micro-arc oxidation (MAO) and its potential for improving the performance of titanium implants in biomedical applications.
Review in Frontiers in bioengineering and biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Specific gene expression patterns associated as reliable biomarkers for predicting dental implant successful osseointegration: a literature review and focused meta-analysis.Frontiers in physiology · 2025Pooled it
- Clinical, Immunological and Microbiological Improvements With Zinc-Coated Healing Abutments During the Healing Phase.International dental journal · 2026Trial
- Antibacterial and Immunomodulatory Coatings for Orthopedic Metal Implants: Biological Rationale, Design Strategies, and Translational Challenges.Advanced healthcare materials · 2026Review
- Construction and Properties of SPI/PLA-PCL Composite Coating on Pure Titanium Surface.Micromachines · 2026Article
- Research Progress in Biomedical Materials.Biomolecules · 2026Review
- Alkaline Ozonation-Induced TiOJournal of functional biomaterials · 2026Article
- Piezoelectric materials for surface modification of titanium-based implants: material design, biological mechanisms, and translational challenges.Frontiers in bioengineering and biotechnology · 2026Review
- Study on the effect and mechanism of gold nanocoated magnesium bone scaffolds for bone repair.BMC musculoskeletal disorders · 2025Article
- Topography-based implants for bone regeneration: Design, biological mechanism, and therapeutics.Materials today. Bio · 2025Review
- Tuning Titanium Surface Properties via μPPEO for Improved Osseointegration and Cell Adhesion.Materials (Basel, Switzerland) · 2025Article
- Microarc Oxidation Coatings Doped with a Low Proportion of Yttrium Enhance the Osseointegration of Titanium Implants through the BMP/Smad Pathway.ACS biomaterials science & engineering · 2025Article
- The rational design, biofunctionalization and biological properties of orthopedic porous titanium implants: a review.Frontiers in bioengineering and biotechnology · 2025Review
- Fabrication and Characterization of Biocompatible Multilayered Elastomer Hybrid with Enhanced Water Permeation Resistance for Packaging of Implantable Biomedical Devices.Micromachines · 2024Article
- Comparative evaluation of Microarc Oxidation and sandblasting on the retention of cement-retained implant restorations: AnJournal of oral biology and craniofacial researchArticle
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Titanium (Ti) and its alloys have good biocompatibility, mechanical properties and corrosion resistance, making them attractive for biomedical applications. However, their biological inertness and lack of antimicrobial properties may compromise the success of implants. In this review, the potential of micro-arc oxidation (MAO) technology to create bioactive coatings on Ti implants is discussed. The review covers the following aspects: 1) different factors, such as electrolyte, voltage and current, affect the properties of MAO coatings; 2) MAO coatings affect biocompatibility, including cytocompatibility, hemocompatibility, angiogenic activity, corrosion resistance, osteogenic activity and osseointegration; 3) antibacterial properties can be achieved by adding copper (Cu), silver (Ag), zinc (Zn) and other elements to achieve antimicrobial properties; and 4) MAO can be combined with other physical and chemical techniques to enhance the performance of MAO coatings. It is concluded that MAO coatings offer new opportunities for improving the use of Ti and its alloys in biomedical applications, and some suggestions for future research are provided.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.