Evidence map›Paper›PMID 38026873›Full record

ArticleFrontiers in bioengineering and biotechnology2023

Cold physical plasma treatment optimization for improved bone allograft processing.

Maximilian Fischer, Emely Bortel, Janosch Schoon, Einar Behnke, Bernhard Hesse, Timm Weitkamp, Sander Bekeschus, Monika Pichler, Georgi I Wassilew, Frank Schulze

Open access · goldAbstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Maximilian FischerCenter for Orthopaedics, Trauma Surgery and Rehabilitation Medicine, University Medicine Greifswald, Greifswald, Germany.
Emely BortelXploraytion GmbH, Berlin, Germany.
Janosch SchoonCenter for Orthopaedics, Trauma Surgery and Rehabilitation Medicine, University Medicine Greifswald, Greifswald, Germany.
Einar BehnkeCenter for Orthopaedics, Trauma Surgery and Rehabilitation Medicine, University Medicine Greifswald, Greifswald, Germany.
Bernhard HesseXploraytion GmbH, Berlin, Germany.
Timm WeitkampSynchrotron SOLEIL, Saint-Aubin, France.
Sander BekeschusZIK Plasmatis, Leibniz Institute for Plasma Science and Technology (INP), Greifswald, Germany.
Monika PichlerCells + Tissuebank Austria Gemeinnützige GmbH, Krems an der Donau, Austria.
Georgi I WassilewCenter for Orthopaedics, Trauma Surgery and Rehabilitation Medicine, University Medicine Greifswald, Greifswald, Germany.
Frank SchulzeCenter for Orthopaedics, Trauma Surgery and Rehabilitation Medicine, University Medicine Greifswald, Greifswald, Germany.
Universitätsmedizin Greifswald · DEEuropean Synchrotron Radiation Facility · FRLeibniz Institute for Plasma Science and Technology · DESynchrotron soleil · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In musculoskeletal surgery, the treatment of large bone defects is challenging and can require the use of bone graft substitutes to restore mechanical stability and promote host-mediated regeneration. The use of bone allografts is well-established in many bone regenerative procedures, but is associated with low rates of ingrowth due to pre-therapeutic graft processing. Cold physical plasma (CPP), a partially ionized gas that simultaneously generates reactive oxygen (O

Indexed as

allograftscancellous bonecold atmospheric pressure plasmamesenchymal stromal cellsplasma medicinesynchrotron radiation computed tomography

Identifiers

PMID38026873
PMCPMC10661279
OpenAlexW4388462739

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.