Evidence map›Paper›PMID 38026842›Full record

ArticleFrontiers in toxicology2023

Advancing chemical safety assessment through an omics-based characterization of the test system-chemical interaction.

Giusy Del Giudice, Giorgia Migliaccio, Nicoletta D'Alessandro, Laura Aliisa Saarimäki, Marcella Torres Maia, Maria Emilia Annala, Jenni Leppänen, Lena Mӧbus, Alisa Pavel, Maaret Vaani and 4 more

Abstract read
In one paragraph

Article in Frontiers in toxicology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Analytical choices drive toxicogenomic potency estimates: a systematic evaluation of transcriptomic points of departure.Toxicological sciences : an official journal of the Society of Toxicology · 2026
    Article
  3. Article
  4. Review
  5. Review
  6. ARACRA: Automated RNA-seq Analysis for Chemical Risk Assessment.Computational and structural biotechnology journal · 2026
    Article
  7. Review
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Giusy Del Giudice *Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Giorgia Migliaccio *Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Nicoletta D'Alessandro *Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Laura Aliisa SaarimäkiFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Marcella Torres MaiaFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Maria Emilia AnnalaFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Jenni LeppänenFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Lena MӧbusFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Alisa PavelFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Maaret VaaniFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Anna ValliusFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Laura Ylä-OutinenFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Dario GrecoFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Angela SerraFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Assessing chemical safety is essential to evaluate the potential risks of chemical exposure to human health and the environment. Traditional methods relying on animal testing are being replaced by 3R (reduction, refinement, and replacement) principle-based alternatives, mainly depending on

Indexed as

AOPchemical-biological interactionchemical safety assessmentmechanism of actionnanosafetynew approach methodologiestest system characterizationtoxicogenomics

Identifiers

PMID38026842
PMCPMC10673692

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.