Evidence map›Paper›PMID 38026821›Full record

ArticleTobacco prevention & cessation2023

Genetic and environmental influences on early-age susceptibility and initiation of nicotine-containing product use: A twin-pairs study.

Andrew Kochvar, Yadi Liu, Marcus Munafo, Zheng Xu, Hongying Daisy Dai

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Tobacco prevention & cessation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Andrew KochvarCollege of Public Health, University of Nebraska Medical Center, Omaha, United States.
Yadi LiuCollege of Public Health, University of Nebraska Medical Center, Omaha, United States.
Marcus MunafoBristol Population Health Science Institute, University of Bristol, Bristol, United Kingdom.
Zheng XuDepartment of Mathematics and Statistics, Wright State University, Dayton, United States.
Hongying Daisy DaiCollege of Public Health, University of Nebraska Medical Center, Omaha, United States.
University of Nebraska Medical Center · USKansas City University · USUniversity of Bristol · GBWright State University · US

Funding

Racial disparities in biomarkers, tobacco cessation, and smoking relapse in association with electronic cigarette useR21DA054818 · NIDA · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI DAI, HONGYING DAISY · 2021 to 2022
$435k
NIDA NIH HHS R21 DA054818
6 · The paper itself

Abstract

introductionNicotine-containing products (NCPs) such as electronic nicotine delivery systems (ENDS) are increasingly common throughout the landscape of youth use of nicotine-containing products (NCP), and have overtaken traditional cigarette smoking modalities. This study seeks to examine the genetic and environmental influences on liability for susceptibility and initiation of ENDS and other NCPs among US children.

methodsData were drawn from 886 monozygotic (MZ) and dizygotic (DZ) twin pairs aged 9-10 years in the Adolescent Brain & Cognitive Development (ABCD) study at the baseline during 2016-2018. Heritability (h

resultsThe national sample included 50% females, 69.5% of non-Hispanic Whites, 12.8% of non-Hispanic Blacks, and 11.6% of Hispanics, with a mean age of 121.5 months. The twin sets were 60% DZ and 40% MZ. Heritability was low for NCP susceptibility (h

conclusionsIn the era with ENDS use surging among youth, NCP initiation remains to be a heritable trait with joint influence from the environment. NCP susceptibility is largely influenced by environmental factors, especially unique environments. Continued assessment of gene × environment interaction can better inform future youth NCP interventions.

Indexed as

ABCD studyenvironmental factorsgenetic factorsheritabilitynicotine-containing product use initiationnicotine-containing product use susceptibility

Identifiers

PMID38026821
PMCPMC10660284
OpenAlexW4388863571

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.