Evidence map›Paper›PMID 38026718›Full record

ArticleOpen access rheumatology : research and reviews2023

Is Serum Uric Acid Level Associated with Disease Activity in Rheumatoid Arthritis Patients.

Dalal Alkhudir, Adeeba Al-Herz, Khulood Saleh, Adel Alawadhi, Waleed Al-Kandari, Eman Hasan, Khaled Mokaddem, Aqeel Ghanem, Youssef Attia Bartella, Mohammed Hussain and 12 more

Open access · goldAbstract read
In one paragraph

Article in Open access rheumatology : research and reviews, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 6 institutions in 1 country.

Dalal AlkhudirDepartment of Rheumatology, Amiri Hospital, Kuwait city, Kuwait.
Adeeba Al-HerzDepartment of Rheumatology, Amiri Hospital, Kuwait city, Kuwait.ORCID 0000-0001-7059-1385
Khulood SalehDepartment of Rheumatology, Farwania Hospital, Farwaniya, Kuwait.
Adel AlawadhiDepartment of Rheumatology, Amiri Hospital, Kuwait city, Kuwait.ORCID 0000-0002-9550-3377
Waleed Al-KandariDepartment of Rheumatology, Farwania Hospital, Farwaniya, Kuwait.ORCID 0000-0002-2710-0963
Eman HasanDepartment of Rheumatology, Amiri Hospital, Kuwait city, Kuwait.
Khaled MokaddemDepartment of Rheumatology, Amiri Hospital, Kuwait city, Kuwait.
Aqeel GhanemDepartment of Rheumatology, Mubarak Al-Kabeer Hospital, Jabriya, Kuwait.
Youssef Attia BartellaDepartment of Rheumatology, Amiri Hospital, Kuwait city, Kuwait.
Mohammed HussainDepartment of Rheumatology, Amiri Hospital, Kuwait city, Kuwait.
Naser AlHadhoodDepartment of Rheumatology, Farwania Hospital, Farwaniya, Kuwait.
Yaser AliDepartment of Rheumatology, Mubarak Al-Kabeer Hospital, Jabriya, Kuwait.ORCID 0000-0002-4721-831X
Ebrahim NaharDepartment of Rheumatology, Mubarak Al-Kabeer Hospital, Jabriya, Kuwait.
Ahmad AleniziDepartment of Rheumatology, Jahra Hospital, Jahra, Kuwait.
Ali AldeiDepartment of Rheumatology, Amiri Hospital, Kuwait city, Kuwait.ORCID 0000-0002-3471-5800
Fatemah AbutibanDepartment of Rheumatology, Jahra Hospital, Jahra, Kuwait.
Sawsan HayatDepartment of Rheumatology, Mubarak Al-Kabeer Hospital, Jabriya, Kuwait.
Hussain BehbehaniDepartment of Rheumatology, Farwania Hospital, Farwaniya, Kuwait.
Fatemah BaronDepartment of Rheumatology, Jahra Hospital, Jahra, Kuwait.
Hebah AlhajeriDepartment of Rheumatology, Mubarak Al-Kabeer Hospital, Jabriya, Kuwait.
Amjad AlkadiDepartment of Rheumatology, Sabah Hospital, Sabah, Kuwait.ORCID 0000-0002-9503-8559
Ahmed AlsaberCollege of Business and Economics, The American University of Kuwait, Salmiya, Kuwait.
Amiri Hospital · KWMubarak Al Kabeer Hospital · KWFarwaniya Hospital · KWJahra Hospital · KWAl-Sabah Hospital · KWAmerican University of Kuwait · KW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: An association between serum uric acid (UA) and disease activity in rheumatoid arthritis (RA) patients has not been well studied. We describe RA patients with high and normal UA and study its association with RA activity. Methods: Adult RA patients from the Kuwait Registry for Rheumatic Diseases (KRRD) were studied from February 2012 through March 2022. Patients with documented UA levels were included. UA of >357 µmol/L (6mg/dL) was considered high. Statistical comparison and correlation were made using multivariate logistic regression. Results: Overall, 1054 patients with documented UA. A total of 158 patients (15%) had high UA level with a mean of 409± 44.4µmol/L. The mean age for the high UA group and low UA group were 59.3 ± 10.7 years and 54.5 ± 12.4 years, respectively ( Conclusion: RA patients with a higher UA had a lower disease activity despite using similar antirheumatic drugs. The reasons behind this association need to be further studied.

Indexed as

DAS28disease activityKRRDKuwaitMiddle Eastregistryrheumatoid arthritisuric acid

Identifiers

PMID38026718
PMCPMC10656862
OpenAlexW4388639949

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.