Evidence map›Paper›PMID 38026692›Full record

ArticleFrontiers in cellular neuroscience2023

Unveiling the interplay between NSAID-induced dysbiosis and autoimmune liver disease in children: insights into the hidden gateway to autism spectrum disorders. Evidence from

Doaa I Mohamed, Hebatallah H Abo Nahas, Asmaa M Elshaer, Dalia Alaa El-Din Aly El-Waseef, Omnyah A El-Kharashi, Soha M Y Mohamed, Yasmine Gamal Sabry, Riyad A Almaimani, Hussain A Almasmoum, Abdulmalik S Altamimi and 5 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. The relationship between neurodevelopmental disorders (NDDs) and NLRP3 inflammasome.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 3 countries.

Doaa I MohamedDepartment of Clinical Pharmacology and Therapeutics, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Hebatallah H Abo NahasPhysiology Department, Faculty of Science, Suez Canal University, Ismailia, Egypt.
Asmaa M ElshaerDepartment of Clinical Pharmacology and Therapeutics, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Dalia Alaa El-Din Aly El-WaseefDepartment of Histology and Cell Biology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Omnyah A El-KharashiDepartment of Clinical Pharmacology and Therapeutics, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Soha M Y MohamedPhysiology Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Yasmine Gamal SabryPhysiology Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Riyad A AlmaimaniDepartment of Biochemistry, Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia.
Hussain A AlmasmoumDepartment of Laboratory Medicine, Faculty of Applied Medical Sciences, Umm Al-Qura University, Makkah, Saudi Arabia.
Abdulmalik S AltamimiDepartment of Pharmaceutical Chemistry, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Alkharj, Saudi Arabia.
Ibrahim Abdel Aziz IbrahimDepartment of Pharmacology and Toxicology, Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia.
Samar Z AlshawwaDepartment of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.
Mariusz JaremkoSmart-Health Initiative and Red Sea Research Center, Division of Biological and Environmental Sciences and Engineering, King Abdullah University of Science and Technology, Thuwal, Saudi Arabia.
Abdul-Hamid EmwasAdvanced Nanofabrication Imaging and Characterization Center, King Abdullah University of Science and Technology, Core Labs, Thuwal, Saudi Arabia.
Essa M SaiedChemistry Department, Faculty of Science, Suez Canal University, Ismailia, Egypt.
Ain Shams University · EGUmm al-Qura University · SAKing Abdullah University of Science and Technology · SAHumboldt-Universität zu Berlin · DEPrince Sattam Bin Abdulaziz University · SAPrincess Nourah bint Abdulrahman University · SASuez Canal University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autism spectrum disorders (ASD) represent a diverse group of neuropsychiatric conditions, and recent evidence has suggested a connection between ASD and microbial dysbiosis. Immune and gastrointestinal dysfunction are associated with dysbiosis, and there are indications that modulating the microbiota could improve ASD-related behaviors. Additionally, recent findings highlighted the significant impact of microbiota on the development of autoimmune liver diseases, and the occurrence of autoimmune liver disease in children with ASD is noteworthy. In the present study, we conducted both an

Indexed as

autism spectrum disordersautoimmune hepatitisclinical studydysbiosisgut microbiotainflammasomesNSAIDsprognostic biomarkers

Identifiers

PMID38026692
PMCPMC10644687
OpenAlexW4388047251

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.