Evidence map›Paper›PMID 38026657›Full record

ArticleFrontiers in veterinary science2023

Kinetics of foot-and-mouth disease vaccine-induced antibody responses in buffaloes (

Juan Manuel Sala, Florencia Celeste Mansilla, María Cruz Miraglia, Sergio Gastón Caspe, Daniel Mariano Perez-Filgueira, Alejandra Victoria Capozzo

Open access · goldAbstract read
In one paragraph

Article in Frontiers in veterinary science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Field Evidence ofVaccines · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Juan Manuel SalaEstación Experimental Agropecuaria, Instituto Nacional de Tecnología Agropecuaria (INTA), Mercedes, Corrientes, Argentina.
Florencia Celeste MansillaInstituto de Virología e Innovaciones Tecnológicas, Centro de Investigaciones en Ciencias Veterinarias y Agronómicas (CICVyA), INTA-Consejo Nacional de Investigaciones Técnicas (CONICET), Hurlingham, Buenos Aires, Argentina.
María Cruz MiragliaInstituto de Virología e Innovaciones Tecnológicas, Centro de Investigaciones en Ciencias Veterinarias y Agronómicas (CICVyA), INTA-Consejo Nacional de Investigaciones Técnicas (CONICET), Hurlingham, Buenos Aires, Argentina.
Sergio Gastón CaspeEstación Experimental Agropecuaria, Instituto Nacional de Tecnología Agropecuaria (INTA), Mercedes, Corrientes, Argentina.
Daniel Mariano Perez-FilgueiraInstituto de Virología e Innovaciones Tecnológicas, Centro de Investigaciones en Ciencias Veterinarias y Agronómicas (CICVyA), INTA-Consejo Nacional de Investigaciones Técnicas (CONICET), Hurlingham, Buenos Aires, Argentina.
Alejandra Victoria CapozzoInstituto de Virología e Innovaciones Tecnológicas, Centro de Investigaciones en Ciencias Veterinarias y Agronómicas (CICVyA), INTA-Consejo Nacional de Investigaciones Técnicas (CONICET), Hurlingham, Buenos Aires, Argentina.
Consejo Nacional de Investigaciones Científicas y Técnicas · ARNational Agricultural Technology Institute · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The role of water buffaloes in foot-and-mouth disease (FMD) epidemiology as one of the major hosts of the virus that can develop persistent asymptomatic infection highlights the importance of sustaining surveillance on the antibody response elicited by vaccination in these animals. There is gap in the knowledge on how serological assays that measure antibodies against capsid proteins perform with buffalo samples and which would be the most reliable test to substitute the virus neutralization test (VNT) a cumbersome and low-throughput tool for field surveillance. Alternatively, the liquid-phase blocking sandwich ELISA (LPBE) is commonly used. Previous data from our laboratory demonstrated that the vaccine-induced antibodies assessed by the LPBE yielded low specificity with buffaloes' samples. In contrast, a single-dilution avidity ELISA (AE) aimed to detect high-avidity antibodies against exposed epitopes, combined with an indirect ELISA (IE) to assess IgG levels, produced more reliable results. Here we analyzed for the first time the kinetics of the antibodies induced by vaccination in two different buffalo herds (

Indexed as

antibody avidityantibody responsebuffaloesfoot and mouth disease virusmaternal immunitypost-vaccination monitoringserology

Identifiers

PMID38026657
PMCPMC10661941
OpenAlexW4388459051

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.