ReviewFrontiers in veterinary science2023
GnRH-immunocastration: an alternative method for male animal surgical castration.
Review in Frontiers in veterinary science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Transcriptomic regulation of the hypothalamic-pituitary axis by GnRH immunization in Xizang sheep.Animal biotechnology · 2026Article
- Coated Bacterial Vaccine Platform Overcomes Weak Antigen Immunogenicity: A Functional Approach to GnRH-Based Immunocastration.Biotechnology journal · 2026Article
- Advances and future applications of immunocastration techniques: a comprehensive review.NPJ vaccines · 2026Review
- A Novel GnRH-Based Immunocastration Vaccine Modulates Growth, Reproductive and Meat Quality Traits in Male Leizhou Goats.Animals : an open access journal from MDPI · 2026Article
- Different Approaches to Caponisation of Cockerels and Their Relation to Welfare.Animals : an open access journal from MDPI · 2026Article
- Transcriptomics identified crucial candidate genes and pathways regulating early testicular development of drakes in the hypothalamic-pituitary-gonadal/thyroid axes.BMC genomics · 2026Article
- Pork Quality and Expression of Genes Involved in Muscularity and Fat Deposition in Different Commercial Lines and Sexes of Pigs.Animals : an open access journal from MDPI · 2025Article
- Preparation of two kinds of immunocastration vaccines and their immune effects on male goats.Animal bioscience · 2025Article
- Technologies and practices to improve feed and nutrient utilization by pigs.Journal of animal science · 2025Review
- Article
- Assessment of the efficacy of a gonadotropin releasing factor (GnRF) analog to suppress ovarian function in gilts under pre-clinical and clinical conditions.Porcine health management · 2024Article
- Behavioral Assessment Reveals GnRH Immunocastration as a Better Alternative to Surgical Castration.Animals : an open access journal from MDPI · 2024Article
- Improving Beef Cattle Production: Safety and Effectiveness of New Immunocastration Vaccine.Animals : an open access journal from MDPI · 2024Article
- Male animal sterilization: history, current practices, and potential methods for replacing castration.Frontiers in veterinary science · 2024Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Castration of male animals is intended to produce high-enhance quality of animal meat, prevent unpleasant taste, reduce aggressive behavior, and manage overbreeding. Over the years, Tranditional methods of mechanical and surgical castration have been employed over the years, but they fall short of meeting animal welfare requirements due to the associated risk of infection, pain, and stress. Immunocastration, specifically Gonadotropin-releasing hormone (GnRH)-immunocastration, targeting the hypothalamic-pituitary-testis (HPT) axis, has emerged as an animal-friendly alternative to surgical castration, effectively addressing these issues. This review seeks to systematically summarize the principles, development, current applications and challenges of GnRH-immunocastration, offering insights into its role in promoting animal welfare.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.