Evidence map›Paper›PMID 38026608›Full record

ArticleClinical ophthalmology (Auckland, N.Z.)2023

Artificial Intelligence Improves Patient Follow-Up in a Diabetic Retinopathy Screening Program.

Eliot R Dow, Karen M Chen, Cindy S Zhao, Austen N Knapp, Anuradha Phadke, Kirsti Weng, Diana V Do, Vinit B Mahajan, Prithvi Mruthyunjaya, Theodore Leng and 1 more

Open access · goldAbstract read
In one paragraph

Article in Clinical ophthalmology (Auckland, N.Z.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

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  15. Modern Approach to Diabetic Retinopathy Diagnostics.Diagnostics (Basel, Switzerland) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Eliot R DowDepartment of Ophthalmology, Byers Eye Institute at Stanford, Palo Alto, CA, USA.
Karen M ChenDepartment of Ophthalmology, Byers Eye Institute at Stanford, Palo Alto, CA, USA.
Cindy S ZhaoDepartment of Ophthalmology, Byers Eye Institute at Stanford, Palo Alto, CA, USA.ORCID 0000-0001-9925-2985
Austen N KnappDepartment of Ophthalmology, Byers Eye Institute at Stanford, Palo Alto, CA, USA.
Anuradha PhadkeDepartment of Internal Medicine, Stanford Health Care, Palo Alto, CA, USA.
Kirsti WengDepartment of Internal Medicine, Stanford Health Care, Palo Alto, CA, USA.
Diana V DoDepartment of Ophthalmology, Byers Eye Institute at Stanford, Palo Alto, CA, USA.
Vinit B MahajanDepartment of Ophthalmology, Byers Eye Institute at Stanford, Palo Alto, CA, USA.ORCID 0000-0003-1886-1741
Prithvi MruthyunjayaDepartment of Ophthalmology, Byers Eye Institute at Stanford, Palo Alto, CA, USA.
Theodore LengDepartment of Ophthalmology, Byers Eye Institute at Stanford, Palo Alto, CA, USA.ORCID 0000-0002-8461-3562
David MyungDepartment of Ophthalmology, Byers Eye Institute at Stanford, Palo Alto, CA, USA.
Smith-Kettlewell Eye Research Institute · USStanford Health Care · USVA Palo Alto Health Care System · US

Funding

Stanford Vision Research CoreP30EY026877 · NEI · STANFORD UNIVERSITY · PI Jeffrey L Goldberg · 2017 to 2026
$8.0M
NEI NIH HHS P30 EY026877
6 · The paper itself

Abstract

Purpose: We examine the rate of and reasons for follow-up in an Artificial Intelligence (AI)-based workflow for diabetic retinopathy (DR) screening relative to two human-based workflows. Patients and Methods: A DR screening program initiated September 2019 between one institution and its affiliated primary care and endocrinology clinics screened 2243 adult patients with type 1 or 2 diabetes without a diagnosis of DR in the previous year in the San Francisco Bay Area. For patients who screened positive for more-than-mild-DR (MTMDR), rates of follow-up were calculated under a store-and-forward human-based DR workflow ("Human Workflow"), an AI-based workflow involving IDx-DR ("AI Workflow"), and a two-step hybrid workflow ("AI-Human Hybrid Workflow"). The AI Workflow provided results within 48 hours, whereas the other workflows took up to 7 days. Patients were surveyed by phone about follow-up decisions. Results: Under the AI Workflow, 279 patients screened positive for MTMDR. Of these, 69.2% followed up with an ophthalmologist within 90 days. Altogether 70.5% ( Conclusion: Ophthalmology follow-up after a positive DR screening result is approximately three-fold higher under the AI Workflow than either the Human Workflow or AI-Human Hybrid Workflow. Improved follow-up behavior may be due to the decreased time to screening result.

Indexed as

deep learningfundus photographymachine learningreferraltelemedicineteleophthalmology

Identifiers

PMID38026608
PMCPMC10665027
OpenAlexW4388153243

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.