Evidence map›Paper›PMID 38026584›Full record

ArticleNeuro-oncology practice2023

Preoperative neurocognitive function as an independent survival prognostic marker in primary glioblastoma.

Evangelia Liouta, Christos Koutsarnakis, Spyridon Komaitis, Aristotelis V Kalyvas, Evangelos Drosos, Juan M García-Gómez, Javier Juan-Albarracín, Vasileios Katsaros, Lampis Stavrinou, George Stranjalis

Abstract readComment
In one paragraph

Article in Neuro-oncology practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Evangelia Liouta1st Department of Neurosurgery, National and Kapodistrian University of Athens, Evangelismos Hospital, Athens, Greece.ORCID https://orcid.org/0000-0003-2948-9631
Christos Koutsarnakis1st Department of Neurosurgery, National and Kapodistrian University of Athens, Evangelismos Hospital, Athens, Greece.ORCID https://orcid.org/0000-0002-1363-5385
Spyridon Komaitis1st Department of Neurosurgery, National and Kapodistrian University of Athens, Evangelismos Hospital, Athens, Greece.ORCID https://orcid.org/0000-0002-7250-414X
Aristotelis V Kalyvas1st Department of Neurosurgery, National and Kapodistrian University of Athens, Evangelismos Hospital, Athens, Greece.ORCID https://orcid.org/0000-0002-0222-488X
Evangelos Drosos1st Department of Neurosurgery, National and Kapodistrian University of Athens, Evangelismos Hospital, Athens, Greece.ORCID https://orcid.org/0000-0002-0456-7317
Juan M García-GómezAthens Microneurosurgery Laboratory, Grupo de Informática Biomédica (IBIME), Instituto de Aplicaciones de las Tecnologías de la Información y de las Comunicaciones Avanzadas (ITACA), Universitat Politècnica de València, Valencia, Spain.
Javier Juan-AlbarracínAthens Microneurosurgery Laboratory, Grupo de Informática Biomédica (IBIME), Instituto de Aplicaciones de las Tecnologías de la Información y de las Comunicaciones Avanzadas (ITACA), Universitat Politècnica de València, Valencia, Spain.
Vasileios KatsarosDepartment of Radiology, General Anti-Cancer and Oncological Hospital of Athens "St. Savvas", Athens, Greece.ORCID https://orcid.org/0000-0003-3087-1475
Lampis Stavrinou2nd Department of Neurosurgery, National and Kapodistrian University of Athens, ATTIKO Hospital, Athens, Greece.
George Stranjalis1st Department of Neurosurgery, National and Kapodistrian University of Athens, Evangelismos Hospital, Athens, Greece.ORCID https://orcid.org/0000-0002-9556-0101

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Aim of the present study is to investigate whether preoperative neurocognitive status is prognostically associated with overall survival (OS) in newly diagnosed glioblastoma (GBM) patients. Methods: Ninety patients with dominant-hemisphere IDH-wild-type GBM were assessed by Mini Mental Status Exam (MMSE), Trail Making Test (TMT) A and B parts, and Control Word Association Test (COWAT) phonemic and semantic subtests. Demographics, Karnofsky Performance Scale, tumor parameters, type of surgery, and adjuvant therapy data were available for patients. Results: According to Cox proportional hazards model the neurocognitive variables of TMT B ( Conclusions: Our study demonstrates that neurocognitive status at baseline-prior to treatment-is an independent prognostic factor for OS in wild-type GBM patients, adding another prognostic tool to assist physicians in selecting the best treatment plan.

Indexed as

cognitionexecutive functionsGBMoverall survivalprognosis

Identifiers

PMID38026584
PMCPMC10666798

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.