ArticleFrontiers in public health2023
Associations between exposure to organophosphate esters and overactive bladder in U.S. adults: a cross-sectional study.
Article in Frontiers in public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 11 citations in OpenAlex.
- Article
- SynergisticiScience · 2026Article
- The positive correlation between parity and overactive bladder in American adults: the mediating effect of body mass index.BMC public health · 2025Article
- The association between urinary cadmium exposure levels and overactive bladder syndrome in the U.S. adults from NHANES database.Scientific reports · 2025Article
- Association of cancer with overactive bladder and impact of overactive bladder on mortality among cancer survivors: NHANES 1999-2018.PloS one · 2025Article
- Association between urinary heavy metal mixtures and overactive bladder risk in the U.S. adult population: a cross-sectional study.Frontiers in public health · 2025Article
- Association between weight-adjusted waist index and overactive bladder syndrome among adult women in the United States: a cross-sectional study.BMC women's health · 2024Article
- Association between life's essential 8 and overactive bladder.Scientific reports · 2024Article
- Association between nocturia and serum albumin in the U.S. adults from NHANES 2005-2012.PloS one · 2024Article
- Associations between serum total bilirubin and overactive bladder from the National Health and Nutrition Examination Survey.Frontiers in endocrinology · 2024Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The relationship between exposure to organophosphate esters (OPEs) and the risk of developing overactive bladder (OAB) is uncertain. The purpose of this study is to examine the potential link between urinary metabolites of organophosphate esters and OAB. Method: Data from the National Health and Nutrition Examination Survey (NHANES) database of the 2011-2016 cycles were utilized. Four urinary metabolites of organophosphate esters: diphenyl phosphate (DPHP), bis (1,3-dichloro-2-propyl) phosphate (BDCPP), bis (2-chloroethyl) phosphate (BCEP), and dibutyl phosphate (DBUP) were included in the study. Multivariate logistic regression and restricted cubic spline (RCS) were used to evaluate the relationship between urinary OPEs metabolites and OAB. Interaction analysis was conducted on subgroups to confirm the findings. Results: A total of 3,443 United States (US) adults aged 20 years or older were included in the study, of whom 597 participants were considered to have OAB. After adjusting for potential confounding factors, we found a positive association between DPHP and the risk of overactive bladder. The risk of overactive bladder increased with increasing DPHP concentrations compared with quartile 1 (quartile 2, OR = 1.19, 95% CI, 0.82-1.73, Conclusion: Our findings indicate that exposure to DPHP could elevate the risk of OAB in US adult females. Further experimental studies are needed to explore the underlying mechanism in the future.
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