Evidence map›Paper›PMID 38026131›Full record

ArticleFrontiers in allergy2023

Evaluation of skin prick location on the forearm using a novel skin prick automated test device.

Sven F Seys, Senne Gorris, Saartje Uyttebroek, Wout Backaert, Mark Jorissen, Rik Schrijvers, Rembert Daems, Dirk Loeckx, Laura Van Gerven, Peter W Hellings

Open access · goldAbstract read
In one paragraph

Article in Frontiers in allergy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Sven F SeysResearch Department, Hippo Dx, Aarschot, Belgium.
Senne GorrisResearch Department, Hippo Dx, Aarschot, Belgium.
Saartje UyttebroekDepartment of Otorhinolaryngology-Head and Neck Surgery, UZ Leuven, Leuven, Belgium.
Wout BackaertDepartment of Otorhinolaryngology-Head and Neck Surgery, UZ Leuven, Leuven, Belgium.
Mark JorissenDepartment of Otorhinolaryngology-Head and Neck Surgery, UZ Leuven, Leuven, Belgium.
Rik SchrijversAllergy and Clinical Immunology Research Group, Department of Microbiology, Immunology & Transplantation, KU Leuven, Leuven, Belgium.
Rembert DaemsResearch Department, Hippo Dx, Aarschot, Belgium.
Dirk LoeckxResearch Department, Hippo Dx, Aarschot, Belgium.
Laura Van GervenDepartment of Otorhinolaryngology-Head and Neck Surgery, UZ Leuven, Leuven, Belgium.
Peter W HellingsDepartment of Otorhinolaryngology-Head and Neck Surgery, UZ Leuven, Leuven, Belgium.
Universitair Ziekenhuis Leuven · BEKU Leuven · BEUniversity of Amsterdam · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The skin prick test (SPT) is the gold standard for identifying allergic sensitization in individuals suspected of having an inhalant allergy. Recently, it was demonstrated that SPT using a novel skin prick automated test (SPAT) device showed increased reproducibility and tolerability compared to the conventional SPT, among other benefits. Objective: This study aimed to evaluate prick location bias using the novel SPAT device. Methods: A total of 118 volunteers were enrolled in this study and underwent SPATs with histamine (nine pricks) and glycerol control (one prick) solutions on the volar side of their forearms. Imaging of the skin reactions was performed using the SPAT device, and the physician determined the longest wheal diameter by visually inspecting the images using a web interface. Prick location bias was assessed along the medial vs. lateral and proximal vs. distal axes of the forearm. Results: In total, 944 histamine pricks were analyzed. Four medial and four lateral histamine pricks were grouped, and wheal sizes were compared. The longest wheal diameters were not significantly different between the medial and lateral prick locations ( Conclusion: The prick location on the volar side of the forearm did not influence wheal size in SPAT-pricked individuals.

Indexed as

allergy diagnosishistamineskin prick teststandardizationwheal

Identifiers

PMID38026131
PMCPMC10646417
OpenAlexW4388127115

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.