Evidence map›Paper›PMID 38026091›Full record

ArticleGerontology & geriatric medicine

Risks and Benefits of Clinical Diagnosis Around the Time of Dementia Onset.

Melinda C Power, Victoria Willens, Christina Prather, Ali Moghtaderi, Yi Chen, Kan Z Gianattasio, Francine Grodstein, Raj C Shah, Bryan D James

Abstract read
In one paragraph

Article in Gerontology & geriatric medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Time to Diagnosis in Dementia: A Systematic Review With Meta-Analysis.International journal of geriatric psychiatry · 2025
    Pooled it
  2. Article
  3. Performance of ICD-10 code-based dementia case definition in the Health and Retirement Study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  4. Article
  5. Patient views on blood-based biomarker tests for Alzheimer's disease in primary care.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Machine learning to detect Alzheimer's disease with data on drugs and diagnoses.The journal of prevention of Alzheimer's disease · 2025
    Article
  10. Article
  11. Regional health priorities for dementia: a roadmap for the Western Pacific.The Lancet regional health. Western Pacific · 2024
    Review
  12. Correlates of missed or late versus timely diagnosis of dementia in healthcare settings.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
  13. Review
  14. 2024 Alzheimer's disease facts and figures.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Melinda C PowerGeorge Washington University, Washington, DC, USA.ORCID https://orcid.org/0000-0001-9099-7964
Victoria WillensGeorge Washington University, Washington, DC, USA.
Christina PratherGeorge Washington University, Washington, DC, USA.
Ali MoghtaderiGeorge Washington University, Washington, DC, USA.
Yi ChenRush University Medical Center, Chicago, IL, USA.
Kan Z GianattasioNORC at the University of Chicago, Bethesda, MD, USA.
Francine GrodsteinRush University Medical Center, Chicago, IL, USA.
Raj C ShahRush University Medical Center, Chicago, IL, USA.ORCID https://orcid.org/0000-0001-9706-9730
Bryan D JamesRush University Medical Center, Chicago, IL, USA.

Funding

Use of Healthcare Across the Full Continuum of Cognitive Health and Decline in Older AdultsR01AG079226 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI Julie PW Bynum, FRANCINE GRODSTEIN · 2022 to 2026
$3.1M
Predictors and consequences of the timing and accuracy of clinical dementia diagnosisR01AG072559 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI Bryan David James · 2022 to 2026
$2.9M
NIA NIH HHS R01 AG072559NIA NIH HHS R01 AG079226
6 · The paper itself

Abstract

Diagnostic delay in dementia is common in the U.S. Drivers of diagnostic delay are poorly understood, but appear related to misconceptions about dementia, stigma, concerns about autonomy, the nature of the diagnostic process, and provider-related factors. There is little quantitative evidence underlying cited risks and benefits of receiving a diagnosis around the time of dementia onset, including impacts on physical health, impacts on mental health, care partner interactions, costs of care, increased time for care planning, or earlier access to treatment. While various groups continue to push for reductions in diagnostic delay, realization of benefits and mitigation of harms will require new research on potential benefits and harms. Workforce and resource constraints, coupled with the expected growth in the number of persons living with dementia, may be a barrier to realization of potential benefits and mitigation of identified harms, which will require adequate access to providers, services, and supports.

Indexed as

caregiving and managementclinical geriatricscognitivie impairmentdementialiterature reviewpublic health/public policy

Identifiers

PMID38026091
PMCPMC10666707

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.