Evidence map›Paper›PMID 38026077›Full record

ArticleJournal of contemporary brachytherapy2023

Assessment of dose to vaginal mucosa for gynecologic template interstitial high-dose-rate brachytherapy using Monte Carlo simulation.

Devin Van Elburg, Tyler Meyer, Kevin Martell, Sarah Quirk, Michael Roumeliotis

Abstract read
In one paragraph

Article in Journal of contemporary brachytherapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Devin Van ElburgDepartment of Physics & Astronomy, University of Calgary, Calgary AB, Canada.
Tyler MeyerDepartment of Physics & Astronomy, University of Calgary, Calgary AB, Canada.
Kevin MartellDepartment of Oncology, Tom Baker Cancer Centre, University of Calgary, Calgary AB, Canada.
Sarah QuirkDepartment of Radiation Oncology, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, USA.
Michael RoumeliotisDepartment of Radiation Oncology & Molecular Radiation Sciences, Johns Hopkins University, Baltimore, MD, USA Institution of research: Tom Baker Cancer Centre, Calgary, AB, Canada, T2N 4N2.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: This study investigated reliable vaginal mucosa dose-volume histogram (DVH) metrics in gynecologic template interstitial high-dose-rate brachytherapy (HDR-BT) for the purpose of standardized dose reporting. Material and methods: Gynecologic template (Syed/Neblett) interstitial HDR-BT patients treated from September 2016 to November 2022 at the study institute were included in the cohort. Each patient implant included a vaginal mucosa contour defined by a 5 mm expansion from vaginal cylinder, then another volume with clinical target volume subtracted. DVH metrics were investigated between D Results: The patient cohort included 61 patients with clinical plans using conventional homogeneous dose calculation (TG43). Heterogeneous vs. water MC dose differences were between -1.1% and -1.4% for all metrics investigated. DVH metrics D Conclusions: For perineal template gynecologic HDR-BT procedures, the 2 cc volume is the smallest representative volume that reliably reports vaginal dose and at minimum should be reported to establish dose and outcome evaluation.

Indexed as

brachytherapydosimetry calculationsgynecologic cancersinterstitial radiotherapy

Identifiers

PMID38026077
PMCPMC10669914

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.