Evidence map›Paper›PMID 38025856›Full record

ArticleRSC advances2023

Highly sensitive detection of circulating tumour cells based on an ASV/CV dual-signal electrochemical strategy.

Gang Wang, Dan Han, Qingyu Zhang

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Gang WangDepartment of Gastroenterology, Tianjin Medical University General Hospital Anshan Road 154, Heping District Tianjin 300052 China zhangqy@tmu.edu.cn.
Dan HanDepartment of Gastroenterology, Tianjin Medical University General Hospital Anshan Road 154, Heping District Tianjin 300052 China zhangqy@tmu.edu.cn.
Qingyu ZhangDepartment of Gastroenterology, Tianjin Medical University General Hospital Anshan Road 154, Heping District Tianjin 300052 China zhangqy@tmu.edu.cn.ORCID https://orcid.org/0000-0001-5162-9755
Tianjin Medical University General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Circulating tumour cells (CTCs), as a tumour marker, may provide more information in early diagnosis and accurate therapy of cancer patients. Electrochemical detection of CTCs has exhibited exceptional advantages. However, single-signal electrochemical detection usually has a high probability of false positives coming from interferents, operating personnel, and nonstandard analytical processes. Herein, a dual-signal strategy using anodic stripping voltammetry (ASV) and cyclic voltammetry (CV) for highly sensitive detection of CTCs was developed. When MCF-7 cells were present, aptamer DNA (DNA1)-magnetic beads (MBs) were captured by CTCs and detached from the biosensing electrodes. Following magnetic separation, polystyrene bead (PS)-CdS QDs labelled on MCF-7 cells were dissolved by HNO

Identifiers

PMID38025856
PMCPMC10631473
OpenAlexW4388489993

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.