Evidence map›Paper›PMID 38025835›Full record

ArticleBiomedical reports2023

Polydatin alleviates sepsis‑induced acute lung injury via downregulation of Spi‑B.

Qingwu Liao, Fang Li, Mingming Xue, Wenan Chen, Zhengang Tao, Yuejiao Song, Ying Yuan

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Qingwu LiaoShanghai Key Laboratory of Perioperative Stress and Protection, Department of Anesthesia, Zhongshan Hospital, Fudan University, Shanghai 200032, P.R. China.
Fang LiDepartment of Geriatrics, Xiamen Branch, Zhongshan Hospital, Fudan University, Xiamen, Fujian 361015, P.R. China.
Mingming XueDepartment of Emergency, Zhongshan Hospital, Fudan University, Shanghai 200032, P.R. China.
Wenan ChenDepartment of Emergency, Zhongshan Hospital, Fudan University, Shanghai 200032, P.R. China.
Zhengang TaoDepartment of Emergency, Zhongshan Hospital, Fudan University, Shanghai 200032, P.R. China.
Yuejiao SongDepartment of Anesthesia, Xiamen Branch, Zhongshan Hospital, Fudan University, Xiamen, Fujian 361015, P.R. China.
Ying YuanDepartment of Geriatrics, Zhongshan Hospital, Fudan University, Shanghai 200032, P.R. China.
Fudan University · CNSun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sepsis-induced acute lung injury (ALI) is related to the dysregulation of inflammatory responses. Polydatin supplement was reported to exhibit anti-inflammatory effects in several diseases. The present study aimed to investigate the role of polydatin in sepsis-induced ALI. A cecum ligation and puncture (CLP)-induced mouse ALI model was established first and the pathological changes of lung tissues were assessed using hematoxylin and eosin staining. Meanwhile, to mimic sepsis-induced ALI

Indexed as

NF-κBPI3K/Aktpolydatinsepsis-induced acute lung injurySpi-B

Identifiers

PMID38025835
PMCPMC10646764
OpenAlexW4387957456

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.