Evidence map›Paper›PMID 38025802›Full record

ArticleJournal of Alzheimer's disease reports2023

Linking Cognitive Impairment with Amyloid-β Accumulation in Alzheimer's Disease: Insights from Behavioral Tests and FTIR Spectroscopy.

Heba Ahmed Gaber, Eman Mohamed Aly, Eman Saad Mohamed, Marwa Elfoly, Mostafa Adel Rabie, Mona Salah Talaat, El-Sayed Mahmoud El-Sayed

Open access · diamondAbstract read
In one paragraph

Article in Journal of Alzheimer's disease reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Heba Ahmed GaberBiophysics and Laser Science Unit, Visual Science Department, Research Institute of Ophthalmology, Giza, Egypt.
Eman Mohamed AlyBiophysics and Laser Science Unit, Visual Science Department, Research Institute of Ophthalmology, Giza, Egypt.ORCID https://orcid.org/0000-0003-0815-3063
Eman Saad MohamedBiophysics and Laser Science Unit, Visual Science Department, Research Institute of Ophthalmology, Giza, Egypt.
Marwa ElfolyOphthalmology Department, Research Institute of Ophthalmology, Giza, Egypt.
Mostafa Adel RabiePharmacology and Toxicology Department, Pharmacy College, Cairo University, Cairo, Egypt.
Mona Salah TalaatBiophysics Department, Science College, Ain Shams University, Cairo, Egypt.
El-Sayed Mahmoud El-SayedBiophysics Department, Science College, Ain Shams University, Cairo, Egypt.
Research Institute of Ophthalmology · EGAin Shams University · EGCairo University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Alzheimer's disease (AD) is a neurodegenerative disorder that progresses over time. Fourier Transform Infrared Spectroscopy (FTIR) analysis gives identification of the main metabolic changes that happen during neurodegeneration, by monitoring biochemical and molecular structure alterations that can help in AD diagnosis or treatment approach. Objective: The aim of the present work is to assess AD hallmarks in molecular structure of retina and monitor accumulation of amyloid beta Methods: AD induced in rats by Aluminum Chloride (AlCl Results: The results indicated that cognitive impairment starting from 6 weeks of AlCl Conclusions: The accumulation of Aβ

Indexed as

AluminumAlzheimer’s diseaseamyloid-βbehavior testchlorideretina

Identifiers

PMID38025802
PMCPMC10657722
OpenAlexW4388288250

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.