ArticlePlastic and reconstructive surgery. Global open2023
Effectiveness of Tranexamic Acid in the Postoperative Period in Body Contour Surgery: Randomized Clinical Trial.
Article in Plastic and reconstructive surgery. Global open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06648265 (IMPACT OF TRANEXAMIC ACID IN TUMESCENT SOLUTION ON POSTOPERATIVE OUTCOMES AFTER LIPOSUCTION), which is not on this map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Impact of tranexamic acid in tumescent solution on postoperative outcomes after liposuction: a double-blind, contralateral arm randomized clinical trial
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- Tranexamic Acid in Liposuction: A Systematic Review of Literature and Meta-Analysis.Aesthetic plastic surgery · 2025Pooled it
- Safety and Efficacy of Tranexamic Acid in Liposuction: A Review of Current Literature.Aesthetic plastic surgery · 2026Review
- The Impact of Combined Intravenous and Topical Tranexamic Acid in Abdominoplasty with Scarpa Fascia Preservation: A Pilot Study.Aesthetic plastic surgery · 2026Article
- International survey on the use of tranexamic acid in plastic surgery-Current practices and perspectives.JPRAS open · 2026Article
- Safety and Efficacy of Combining Multiple Body-Contouring Procedures in Massive-Weight-Loss Patients: A Retrospective Multicenter Study.Aesthetic plastic surgery · 2026Article
- Perioperative Tranexamic Acid Reduces Bleeding and Wound Complications in Post-Bariatric Abdominoplasty: A Retrospective Cohort Study.Life (Basel, Switzerland) · 2026Article
- Effectiveness of Tranexamic Acid in Postbariatric Surgery Abdominoplasty: Improving Hemostasis and Recovery Outcomes.Plastic and reconstructive surgery. Global open · 2026Article
- Abdominoplasty After Weight Loss in Post-bariatric Surgery: An Optimized Surgery Procedure and Clinical Protocol-A Large Single-center Study.Aesthetic plastic surgery · 2025Article
- Topical Application of Tranexamic Acid in Abdominoplasties Leads to Lower Drainage Volume and Earlier Drain Removal.Plastic and reconstructive surgery. Global open · 2025Article
- Muscular Increase and Definition of the Back Contour Through Key Fat Grafting and Liposuction.Aesthetic surgery journal. Open forum · 2025Article
- Tranexamic acid in hip and spine surgery for children with cerebral palsy - a PRISMA-compliant scoping review.Systematic reviews · 2024Article
- Systemic Tranexamic Acid for Reduced Postoperative Blood Loss and Less Bleeding Complications in Fleur-de-lis Abdominoplasty and Apronectomy.Aesthetic plastic surgery · 2024Article
- The Use of Tranexamic Acid in Breast Reduction and Abdominoplasty: A Review of a Multicenter Federated Electronic Health Record Database.Aesthetic surgery journal. Open forum · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Tranexamic acid (TXA) is used to reduce bleeding in body contouring procedures; however, there are no studies that show the effectiveness of TXA when it is also used in the immediate postoperative period. Methods: A controlled, randomized, parallel, and open-label clinical trial was carried out in adult patients undergoing liposculpture and/or abdominoplasty. A control group administering presurgical TXA and a study group with presurgical and postsurgical TXA were formed. The decrease in hemoglobin and the incidence of blood transfusions between both groups were compared as well as the possible adverse effects of TXA. Results: Four hundred twenty-seven subjects were included, 208 (48.7%) in the control group and 219 (51.3%) in the study group. The median age was 34 years (interquartile range 28-42). Median postoperative hemoglobin levels at 24 hours were similar in both groups (study 11.3 g/dL versus control 11.1 g/dL, Conclusion: TXA proved to be more effective in reducing intra- and postsurgical bleeding and the need for transfusions, when used preoperatively and continued for 48 hours after surgery, than when used only preoperatively, without reporting adverse or thromboembolic effects.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.