Central airway squamous metaplasia following radiation therapy mimicking local tumour recurrence.

Jonathan Arulanantham, Revadhi Chelvarajah, A Kasim Ismail, Victoria J Bray, Shalini K Vinod, Jonathan P Williamson

Open access · goldAbstract readCase Reports

In one paragraph

Article in Respiratory medicine case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact, top 60% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Jonathan ArulananthamFaculty of Medicine Health and Human Sciences, Macquarie University, Balaclava Road, Macquarie Park, NSW, 2019, Australia.

Revadhi ChelvarajahLiverpool Cancer Therapy Centre, Liverpool Hospital, Campbell Street, Liverpool, NSW, 2170, Australia.

A Kasim IsmailLiverpool Hospital, Anatomical Pathology, Campbell Street, Liverpool, NSW, 2170, Australia.

Victoria J BrayLiverpool Cancer Therapy Centre, Liverpool Hospital, Campbell Street, Liverpool, NSW, 2170, Australia.

Shalini K VinodLiverpool Cancer Therapy Centre, Liverpool Hospital, Campbell Street, Liverpool, NSW, 2170, Australia.

Jonathan P WilliamsonFaculty of Medicine Health and Human Sciences, Macquarie University, Balaclava Road, Macquarie Park, NSW, 2019, Australia.

Liverpool Hospital · AUCamden and Campbelltown Hospitals · AUNorthern Health · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radiation therapy can result in injury to the lung parenchyma and central airways; the latter is less well documented in the literature. Here, we describe a 65-year-old Caucasian male, who developed focal endobronchial nodules and right main bronchial stenosis suggesting tumour recurrence, 32 months following curative intent concurrent chemoradiation therapy for Stage 3B squamous cell carcinoma of the lung. Computed tomography and positron emission tomography results are detailed. Flexible bronchoscopy with bronchial biopsies revealed squamous metaplasia rather than malignant tumour recurrence, with ongoing observation planned.

Indexed as

Chemoradiation therapyCOPDNon-small cell lung cancerRespiratory structure and functionSmokingSquamous Metaplasia

Identifiers

PMID38025247

DOI10.1016/j.rmcr.2023.101942

PMCPMC10665950

OpenAlexW4388248548

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC-ND

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.