ArticleFrontiers in chemistry2023
Graphene quantum dots promote migration and differentiation of periodontal ligament stem cells.
Article in Frontiers in chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Microenvironment-mediated stem cell fate in periodontal tissue remodeling and repair.Bioactive materials · 2026Review
- Graphene quantum dots remodel osteogenesis of human periodontal ligament stem cells under inflammatory microenvironment: anFrontiers in bioengineering and biotechnology · 2026Article
- Quantum dots in periodontology: emerging promise and translational challenges.Frontiers in dental medicine · 2026Review
- The impact of graphene quantum dots on osteogenesis potential of Wharton's jelly mesenchymal stem cells in fibrin hydrogel scaffolds.Cytotechnology · 2025Article
- Enhancing bone tissue engineering with polyacrylonitrile electrospun scaffolds and graphene quantum dots: A comprehensive approach to regenerative medicine.BioImpacts : BI · 2025Article
- Unlocking tiny titans: 360 view of the quantum dots nanotechnology for dental applications.Frontiers in dental medicine · 2025Review
- Polyphenols-based intelligent oral barrier membranes for periodontal bone defect reconstruction.Regenerative biomaterials · 2024Article
- Polyethylenimine-modified graphene quantum dots promote endothelial cell proliferation.Regenerative biomaterials · 2024Article
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7 authors.
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Abstract
Graphene and its derivatives have attracted much attention as nanomaterials in bone tissue engineering because of their remarkable ability to induce cell osteogenic differentiation. However, graphene quantum dots (GQDs), as graphene derivatives, little is known about their osteodifferentiation- and osteoinduction-promoting capabilities, especially in the restoration of bone defect caused by periodontitis. Therefore, there is a growing need to investigate the effect of GQDs on periodontal ligament stem cells (PDLSCs). Here, we postulated that GQDs are a promising biocompatible nanomaterial that facilitated the migration and differentiation of PDLSCs, and use laboratory methods like CCK-8, transwell experiments, qRT-PCR, Alizarin red staining and immunofluorescence staining to evaluate. Our experiments confirmed that GQDs did not inhibit cell viability, with most cells remaining viable even at GQDs concentrations of up to 30 μg mL
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