ArticleBiochemistry and biophysics reports2023
Circular RNAs in atrial fibrillation: From bioinformatics analysis of circRNA-miRNA-mRNA network to serum expression.
Article in Biochemistry and biophysics reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Article
- Epigenetic Drivers of Atrial Fibrillation: Mechanisms, Biomarkers, and Therapeutic Targets.International journal of molecular sciences · 2025Review
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Authors and funding
5 authors.
Funding
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Abstract
Atrial fibrillation (AF) is a common arrhythmia in clinical practice, and its incidence is increasing year by year, which seriously affects the survival and prognosis of patients. In recent years, circRNAs has played an important role in the diagnosis and treatment of AF. The purpose of this study was to search for differentially expressed circRNAs(DEcircRNAs) in the serum of AF patients by analyzing the expression profile of existing chips, combining bioinformatics technology and in vitro experiments, and to explore the regulatory mechanism of circRNAs in the occurrence and development of AF. By using the AF datasets in the Gene expression omnibus (GEO) database, serum samples of patients with AF were collected, and the expression level of selected circRNAs was verified by qPCR. We found that the expression of four circRNAs was increased in the serum of patients with AF, suggesting that these four DEcircRNAs may be used as auxiliary diagnostic markers for AF. Bioinformatics predicts the related signaling pathways that differentially expressed genes may regulate in the occurrence and development of AF, providing a new theoretical basis for the molecular mechanism of the occurrence of atrial fibrillation and auxiliary diagnostic targets.
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