Evidence map›Paper›PMID 38024652›Full record

ArticleJournal of the Endocrine Society2023

The Degree of Prepregnancy Vitamin D Deficiency Is Not Associated With Gestational Diabetes in Women Undergoing ART.

Yvonne Liu, Johann-Georg Hocher, Huijun Chen, Liang Hu, Xiaoli Zhang, Sufen Cai, Sha Tang, Fei Gong, Bernhard K Krämer, Ge Lin and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the Endocrine Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Observational
  3. Article
  4. Article
  5. Article
  6. Observational
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Yvonne LiuFifth Department of Medicine (Nephrology/Endocrinology/Rheumatology/Pneumology), University Medical Centre Mannheim, University of Heidelberg, 68167 Mannheim, Germany.
Johann-Georg HocherFifth Department of Medicine (Nephrology/Endocrinology/Rheumatology/Pneumology), University Medical Centre Mannheim, University of Heidelberg, 68167 Mannheim, Germany.
Huijun ChenFifth Department of Medicine (Nephrology/Endocrinology/Rheumatology/Pneumology), University Medical Centre Mannheim, University of Heidelberg, 68167 Mannheim, Germany.
Liang HuDepartment of Clinical Science, Reproductive and Genetic Hospital of CITIC-Xiangya, Changsha 410008, China.
Xiaoli ZhangFifth Department of Medicine (Nephrology/Endocrinology/Rheumatology/Pneumology), University Medical Centre Mannheim, University of Heidelberg, 68167 Mannheim, Germany.ORCID https://orcid.org/0000-0003-0076-0854
Sufen CaiDepartment of Clinical Science, Reproductive and Genetic Hospital of CITIC-Xiangya, Changsha 410008, China.
Sha TangDepartment of Clinical Science, Reproductive and Genetic Hospital of CITIC-Xiangya, Changsha 410008, China.
Fei GongDepartment of Clinical Science, Reproductive and Genetic Hospital of CITIC-Xiangya, Changsha 410008, China.ORCID https://orcid.org/0000-0002-9869-5669
Bernhard K KrämerFifth Department of Medicine (Nephrology/Endocrinology/Rheumatology/Pneumology), University Medical Centre Mannheim, University of Heidelberg, 68167 Mannheim, Germany.
Ge LinDepartment of Clinical Science, Reproductive and Genetic Hospital of CITIC-Xiangya, Changsha 410008, China.ORCID https://orcid.org/0000-0002-3877-2546
Berthold HocherFifth Department of Medicine (Nephrology/Endocrinology/Rheumatology/Pneumology), University Medical Centre Mannheim, University of Heidelberg, 68167 Mannheim, Germany.ORCID https://orcid.org/0000-0001-8143-0579
Central South University · CNHeidelberg University · DECharles University · CZReproductive & Genetic Hospital CITIC-Xiangya · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Context: Gestational diabetes mellitus (GDM) is a common pregnancy complication, particularly in women undergoing assisted reproductive technology (ART). An association of GDM with vitamin D in women conceiving naturally has been described; however, studies have yielded heterogeneous results. Objective: To analyze the association between prepregnancy total and free vitamin D and GDM incidence in women undergoing ART. Methods: Post hoc analysis of a prospective study at the Reproductive and Genetic Hospital of CITIC-Xiangya in Changsha, China. Total and free vitamin D were measured 1 day before embryo transfer. The patients were screened for GDM using the oral glucose tolerance test. Results: A total of 1593 women were included in the study, among whom 256 (16.1%) developed GDM. According to international guidelines for total 25-hydroxyvitamin D [25(OH)D], 47 (2.9%) patients had sufficient (≥30 ng/mL) levels, while 696 (43.7%) were insufficient (20 to <30 ng/mL) and 850 (54.4%) were deficient (<20 ng/mL). Comparing GDM and non-GDM patients, there was no significant difference in total nor free vitamin D levels ( Conclusion: In this relatively vitamin D deficient/insufficient ART cohort, the degree of neither total nor free vitamin D deficiency before pregnancy was associated with the occurrence of GDM.

Indexed as

free vitamin Dgestational diabetesin vitro fertilizationvitamin D

Identifiers

PMID38024652
PMCPMC10681737
OpenAlexW4388590898

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.