Evidence map›Paper›PMID 38024651›Full record

ArticleJournal of the Endocrine Society2023

Association of Endocrine Disrupting Chemicals With the Metabolic Syndrome Among Women in the Multiethnic Cohort Study.

Ugonna Ihenacho, Cherie Guillermo, Lynne R Wilkens, Adrian A Franke, Chiuchen Tseng, Yuqing Li, Meera Sangaramoorthy, Mindy C Derouen, Christopher A Haiman, Daniel O Stram and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the Endocrine Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Ugonna IhenachoDepartment of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA.ORCID https://orcid.org/0000-0002-9469-8184
Cherie GuillermoPopulation Sciences in the Pacific Program, University of Hawaii Cancer Center, Honolulu, HI 96813, USA.ORCID https://orcid.org/0000-0002-0596-1615
Lynne R WilkensPopulation Sciences in the Pacific Program, University of Hawaii Cancer Center, Honolulu, HI 96813, USA.ORCID https://orcid.org/0000-0001-8408-4536
Adrian A FrankeCancer Biology Program, University of Hawaii Cancer Center, Honolulu, HI 96813, USA.ORCID https://orcid.org/0000-0002-1911-1662
Chiuchen TsengDepartment of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA.
Yuqing LiDepartment of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA 94158, USA.
Meera SangaramoorthyDepartment of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA 94158, USA.
Mindy C DerouenDepartment of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA 94158, USA.ORCID https://orcid.org/0000-0002-7198-7629
Christopher A HaimanDepartment of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA.ORCID https://orcid.org/0000-0002-0097-9971
Daniel O StramDepartment of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA.ORCID https://orcid.org/0000-0001-7099-9022
Loïc Le MarchandPopulation Sciences in the Pacific Program, University of Hawaii Cancer Center, Honolulu, HI 96813, USA.ORCID https://orcid.org/0000-0001-5013-980X
Iona ChengDepartment of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA 94158, USA.ORCID https://orcid.org/0000-0003-4132-2893
Anna H WuDepartment of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA.ORCID https://orcid.org/0000-0003-0546-902X
University of Southern California · USUniversity of California, San Francisco · USUniversity of Hawaiʻi at Mānoa · US

Funding

USC/NORRIS COMPREHENSIVE CANCER CENTER (CORE) SUPPORTP30CA014089 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Fumito Ito · 1985 to 2026
$181.4M
University of Hawaii Cancer Center CCSGP30CA071789 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI Xin Chen · 1996 to 2026
$56.2M
Translational Research Support CoreP30ES007048 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Joseph Leo Wiemels · 1996 to 2026
$46.4M
Understanding Population Differences in Cancer: The MEC StudyU01CA164973 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI HAIMAN, CHRISTOPHER ALAN, LE MARCHAND, LOIC · 2015 to 2025
$37.4M
Multidisciplinary Training in Ethnic Diversity and Cancer DisparitiesT32CA229110 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI HAIMAN, CHRISTOPHER ALAN, LE MARCHAND, LOIC · 2019 to 2023
$2.1M
NCI NIH HHS P30 CA014089NCI NIH HHS P30 CA071789NCI NIH HHS T32 CA229110NCI NIH HHS U01 CA164973NIEHS NIH HHS P30 ES007048
6 · The paper itself

Abstract

Metabolic syndrome (MetS) is associated with a high risk of cardiovascular disease, a leading cause of death among women. MetS is a diagnosis of at least 3 of the following: high blood pressure, high fasting glucose, high triglycerides, high waist circumference, and low high-density lipoprotein cholesterol. Epidemiological studies suggest that endocrine disrupting chemical (EDC) exposure is positively associated with individual components of MetS, but evidence of an association between EDCs and MetS remains inconsistent. In a cross-sectional analysis within the Multiethnic Cohort Study, we evaluated the association between 4 classes of urinary EDCs (bisphenol A [BPA], triclosan, parabens, and phthalates) and MetS among 1728 women. Multivariable logistic regression was used to estimate odds ratios and 95% CI for the association between tertiles of each EDC and MetS adjusting for age, body mass index (BMI), racial and ethnic group, and breast cancer status. Stratified analyses by race and ethnicity and BMI were conducted. MetS was identified in 519 (30.0%) women. We did not detect statistically significant associations of MetS with BPA, triclosan, or phthalate metabolite excretion. MetS was inversely associated with total parabens (

Indexed as

bisphenol Ametabolic syndromemultiethnicparabensphthalatetriclosan

Identifiers

PMID38024651
PMCPMC10666661
OpenAlexW4388775367

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.