ArticleEJHaem2023
Prognostic heterogeneity and clonal dynamics within distinct subgroups of myelodysplastic syndrome and acute myeloid leukemia with
Registry-linked trialOpen access · diamondAbstract read
In one paragraph
Article in EJHaem, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07094464 (A Single-Arm, Open-Label Phase I Clinical Study of Selinexor Combined With Azacitidine for Maintenance Therapy in TP53 Mutant AML/MDS Patients Post-Transplant), which is not on this map. Cited by 17 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
6.4field-weighted citation impact, top 3% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
NCT07094464 phase1active not recruitingnot on this mapstarted 2025, after this paper: background citation
A Single-Arm, Open-Label Phase I Clinical Study of Selinexor Combined With Azacitidine for Maintenance Therapy in TP53 Mutant AML/MDS Patients Post-Transplant
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Effects of donor-engrafted clonal hematopoiesis in allogeneic and autologous stem cell transplantation: a systematic review and meta-analysis.Bone marrow transplantation · 2024Pooled it
- Treatment ofHaematologica · 2026Trial
- Determinants of survival after failure of frontline venetoclax plus hypomethylating agent therapy in 356 patients with newly diagnosed acute myeloid leukemia.Blood cancer journal · 2026Article
- Modern Concepts in Precision Targeting of Acute Myeloid Leukemia Based on Principles of Molecular Oncology.Cancers · 2026Review
- Prognostic impact of intensive chemotherapy in patients with TP53-mutated AML.Blood cancer journal · 2026Article
- Clinico-genomic characterization of RAS-mutant acute myeloid leukemia.Annals of hematology · 2026Article
- Portraits of clonal hematopoiesis in DNMT3A/TET2/ASXL1-mutant myelodysplastic neoplasms and acute myeloid leukemia.Annals of hematology · 2026Article
- Prognosis of Acute Myeloid Leukemia Based on TP53 Mutation Among Adult Patients: A Systematic Review and Meta-Analysis.Iranian journal of pathology · 2026Review
- The evolving nosology of myeloid neoplasms: the semi-centennial of the 1976 French-American-British classification.Leukemia · 2025Review
- Molecular predictors of response and survival in patients with relapsed/refractory acute myeloid leukemia following venetoclax plus hypomethylating agent therapy.Haematologica · 2025Article
- Venetoclax added to CLAG regimen might improve the outcome of patients with relapsed/refractory acute myeloid leukemia.Therapeutic advances in hematology · 2025Article
- Development and validation of a disulfidptosis-related genes signature for predicting outcomes and immunotherapy in acute myeloid leukemia.Frontiers in immunology · 2025Article
- Review
- Natural history of clonal haematopoiesis seen in real-world haematology settings.British journal of haematology · 2024Article
- The immunobiology of myelodysplastic neoplasms: a mini-review.Frontiers in immunology · 2024Review
- Editorial: Immunobiology and immunotherapeutics in myelodysplastic syndrome and acute myeloid leukemia.Frontiers in immunology · 2024Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
19 authors at 3 institutions in 2 countries.
Shyam A PatelDivision of Hematology and Oncology, Department of Medicine UMass Memorial Medical Center, UMass Chan Medical School Worcester Massachusetts United States.ORCID https://orcid.org/0000-0002-8208-1902
Jan CernyDivision of Hematology and Oncology, Department of Medicine UMass Memorial Medical Center, UMass Chan Medical School Worcester Massachusetts United States.ORCID https://orcid.org/0000-0002-6602-5505
William K GerberDivision of Hematology and Oncology, Department of Medicine UMass Memorial Medical Center, UMass Chan Medical School Worcester Massachusetts United States.
Muthalagu RamanathanDivision of Hematology and Oncology, Department of Medicine UMass Memorial Medical Center, UMass Chan Medical School Worcester Massachusetts United States.
Asiri EdiriwickremaInstitute for Stem Cell Biology & Regenerative Medicine; Division of Hematology, Department of Medicine Stanford University Stanford California United States.ORCID https://orcid.org/0000-0002-6480-8290
Benjamin TanenbaumDivision of Hematology and Oncology, Department of Medicine UMass Memorial Medical Center, UMass Chan Medical School Worcester Massachusetts United States.
Lloyd HutchinsonDepartment of Pathology UMass Memorial Medical Center, UMass Chan Medical School Worcester Massachusetts United States.
Xiuling MengDepartment of Pathology UMass Memorial Medical Center, UMass Chan Medical School Worcester Massachusetts United States.
Julie FlahiveDepartment of Population & Quantitative Health Sciences UMass Chan Medical School Worcester Massachusetts United States.
Bruce BartonDepartment of Population & Quantitative Health Sciences UMass Chan Medical School Worcester Massachusetts United States.
Andrew J Gillis-SmithDivision of Hematology and Oncology, Department of Medicine UMass Memorial Medical Center, UMass Chan Medical School Worcester Massachusetts United States.
Sakiko SuzukiDivision of Hematology and Oncology, Department of Medicine UMass Memorial Medical Center, UMass Chan Medical School Worcester Massachusetts United States.
Salwa KhedrDepartment of Pathology UMass Memorial Medical Center, UMass Chan Medical School Worcester Massachusetts United States.
William SeloveDepartment of Pathology UMass Memorial Medical Center, UMass Chan Medical School Worcester Massachusetts United States.ORCID https://orcid.org/0000-0002-2736-2912
Anne W HigginsDepartment of Pathology UMass Memorial Medical Center, UMass Chan Medical School Worcester Massachusetts United States.
Patricia M MironDepartment of Pathology UMass Memorial Medical Center, UMass Chan Medical School Worcester Massachusetts United States.
Karl SiminDept. of Molecular Cell & Cancer Biology UMass Chan Medical School Worcester Massachusetts United States.
Bruce WodaDepartment of Pathology UMass Memorial Medical Center, UMass Chan Medical School Worcester Massachusetts United States.
Jonathan M GerberDivision of Hematology and Oncology, Department of Medicine UMass Memorial Medical Center, UMass Chan Medical School Worcester Massachusetts United States.
UMass Memorial Health Care · USUniversity of Massachusetts Chan Medical School · USCalifornia Institute for Regenerative Medicine · US
Funding
University of Massachusetts Center for Clinical Science and Translational SupplementUL1TR001453 · NCATS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI LUZURIAGA, KATHERINE F · 2015 to 2024
$39.0MSingle cell characterization of human acute myeloid leukemiaF32CA250304 · NCI · STANFORD UNIVERSITY · PI EDIRIWICKREMA, ASIRI · 2020 to 2022
$254kNCATS NIH HHS UL1 TR001453NCI NIH HHS F32 CA250304
Abstract
PubMed holds no abstract for this paper.
Indexed as
acute myeloid leukemiaclonal dynamicshematopoietic stem cellmyelodysplastic syndromeTP53
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
NCT07094464ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.