Evidence map›Paper›PMID 38024624›Full record

ArticleEJHaem2023

A comparison of the prognostic performance of the Lugano 2014 and RECIL 2017 response criteria in patients with NHL from the phase III GOYA and GALLIUM trials.

Lale Kostakoglu, Maurizio Martelli, Laurie H Sehn, Andrew Davies, Marek Trněný, Michael Herold, Umberto Vitolo, Wolfgang Hiddemann, Judith Trotman, Andrea Knapp and 6 more

Abstract read
In one paragraph

Article in EJHaem, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Lale KostakogluDepartment of Radiology and Medical Imaging University of Virginia Charlottesville Virginia USA.ORCID https://orcid.org/0000-0002-2419-348X
Maurizio MartelliHematology, Department of Translational and Precision Medicine Sapienza University Rome Italy.
Laurie H SehnBC Cancer Center for Lymphoid Cancer and the University of British Columbia Vancouver British Columbia Canada.
Andrew DaviesCancer Research UK Centre/NIHR Experimental Cancer Medicine Centre University of Southampton Southampton UK.
Marek Trněný1st Faculty of Medicine Charles University General Hospital Prague Czech Republic.
Michael HeroldHELIOS-Klinikum Erfurt Erfurt Germany.
Umberto VitoloMedical Oncology, Candiolo Cancer Institute, FPO-IRCCS Candiolo Italy.ORCID https://orcid.org/0000-0001-7772-2747
Wolfgang HiddemannUniversity Hospital Munich Munich Germany.
Judith TrotmanConcord Repatriation General Hospital, University of Sydney Concord New South Wales Australia.
Andrea KnappF. Hoffmann-La Roche Ltd Basel Switzerland.
Federico MattielloF. Hoffmann-La Roche Ltd Basel Switzerland.
Tina G NielsenF. Hoffmann-La Roche Ltd Basel Switzerland.
Deniz SahinF. Hoffmann-La Roche Ltd Basel Switzerland.
Gila SellamF. Hoffmann-La Roche Ltd Basel Switzerland.
Carol WardF. Hoffmann-La Roche Ltd Basel Switzerland.
Anas YounesMemorial Sloan Kettering Cancer Center New York City New York USA.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

The Lugano 2014 criteria are the standard for response assessment in lymphoma. We compared the prognostic performance of Lugano 2014 and the more recently developed response evaluation criteria in lymphoma (RECIL 2017), which relies primarily on computed tomography and uses unidimensional measurements, in patients with previously untreated diffuse large B-cell lymphoma (DLBCL) and follicular lymphoma (FL) from the phase III GOYA and GALLIUM trials, respectively. Concordance between responses according to the Lugano 2014 and RECIL 2017 criteria was analyzed. Landmark analyses of progression-free survival (PFS) and overall survival (OS) by end of treatment (EOT) and end of induction (EOI) response status according to RECIL 2017 and Lugano 2014 criteria, and prognostic value of response at EOT/EOI were also compared. Overall, 1333 patients were included from GOYA and 502 from GALLIUM. Complete response (CR) status according to RECIL 2017 criteria showed high concordance with complete metabolic response (CMR) status by Lugano 2014 criteria in both GOYA (92.5%) and GALLIUM (92.4%). EOT and EOI CR/CMR status by both criteria was highly prognostic for PFS in GOYA (RECIL 2017 [CR]: hazard ratio [HR], 0.35 [95% confidence interval [CI] 0.26-0.46]; Lugano 2014 [CMR]: HR, 0.35 [95% CI 0.26-0.48]; both

Indexed as

GALLIUMGOYALugano 2014NHLRECIL 2017response criteria

Identifiers

PMID38024624
PMCPMC10660391

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.