Evidence map›Paper›PMID 38024557›Full record

ArticleJID innovations : skin science from molecules to population health2023

Cutaneous Hypervascularization Treatment Using Photo-Mediated Ultrasound Therapy.

Mingyang Wang, Rohit Singh, Wei Zhang, Jeffrey S Orringer, Yannis M Paulus, Xinmai Yang, Xueding Wang

Abstract read
In one paragraph

Article in JID innovations : skin science from molecules to population health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Photo-Mediated Ultrasound Therapy (PUT) for the Treatment of Deep Cutaneous Vasculature.IEEE open journal of ultrasonics, ferroelectrics, and frequency control · 2025
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mingyang WangDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, USA.
Rohit SinghPhotoSonoX LLC, Ann Arbor, Michigan, USA.
Wei ZhangDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, USA.
Jeffrey S OrringerDepartment of Dermatology, University of Michigan, Ann Arbor, Michigan, USA.
Yannis M PaulusDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, USA.
Xinmai YangInstitute for Bioengineering Research, University of Kansas, Lawrence, Kansas, USA.
Xueding WangDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, USA.

Funding

VIVARIUM MODULEP30EY007003 · NEI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI James D Weiland · 1987 to 2026
$17.6M
Precisely removing microvessels by photo-mediated ultrasound therapyR01EY029489 · NEI · UNIVERSITY OF KANSAS LAWRENCE · PI YANG, XINMAI · 2018 to 2021
$1.8M
Real-time In Vivo Visualization of the Molecular Processes in Choroidal NeovascularizationK08EY027458 · NEI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PAULUS, YANNIS MANTAS · 2018 to 2021
$898k
Photo-mediated ultrasound therapy for treatment of cutaneous vascular malformationsR41EB030875 · NIBIB · PHOTOSONOX LLC · PI WANG, XUEDING, YANG, XINMAI · 2020 to 2020
$325k
Novel Nanosecond Laser and Ultrasound to Selectively Treat Eye Blood VesselsR41EY031219 · NEI · PHOTOSONOX LLC · PI PAULUS, YANNIS MANTAS · 2020 to 2020
$225k
NEI NIH HHS K08 EY027458NEI NIH HHS P30 EY007003NEI NIH HHS R01 EY029489NEI NIH HHS R41 EY031219NIBIB NIH HHS R41 EB030875
6 · The paper itself

Abstract

Photo-mediated ultrasound therapy (PUT) is a cavitation-based, highly selective antivascular technique. In this study, the effectiveness and safety of PUT on cutaneous vascular malformation was examined through in vivo experiments in a clinically relevant chicken wattle model, whose microanatomy is similar to that of port-wine stain and other hypervascular dermal diseases in humans. Assessed by optical coherence tomography angiography, the blood vessel density in the chicken wattle decreased by 73.23% after one session of PUT treatment in which 0.707 J/cm

Identifiers

PMID38024557
PMCPMC10661455

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.