Evidence map›Paper›PMID 38023960›Full record

ArticleGerms2023

A rare presentation of infectious mononucleosis: cholestatic hepatitis with hyperbilirubinemia.

Aldin Jerome, Vatsal Khanna, Elisa Akagi, Ashish Bhargava

Open access · greenAbstract readCase Reports
In one paragraph

Article in Germs, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Traveling with chronic viral hepatitis.Tropical diseases, travel medicine and vaccines · 2026
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Aldin JeromeMD. Department of Medicine, Wayne State University SOM/Ascension Providence Rochester Hospital, 1101 W. University Dr, Rochester, MI 48307, USA.
Vatsal KhannaMD, Department of Medicine, Wayne State University SOM/Ascension Providence Rochester Hospital, 1101 W. University Dr, Rochester, MI 48307, USA.
Elisa AkagiMD, Department of Medicine, Ascension St. John Hospital, 22101 Moross Rd, Grosse Pointe Woods, MI 48236, USA.
Ashish BhargavaMD, FACP, FIDSA, Department of Medicine, Thomas Mackey Center for Infectious Disease Research, Ascension St. John Hospital. 22101 Moross Rd, Grosse Pointe Woods, MI 48236, USA.
Providence Hospital · USSt. John Hospital & Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Epstein-Barr virus infection with mononucleosis is the most common presentation in young adults. Most infections are self-limited, although in a few cases complications can include serious conditions such as lymphoproliferative disorders or in less severe cases, mild hepatitis. Case report: We present an unusual case of a young male with no liver disease, who presented with markedly elevated cholestatic pattern hyperbilirubinemia, as well as hepatitis. The patient responded well to symptomatic treatments, with spontaneous improvement of the hyperbilirubinemia and transaminitis. Conclusions: Epstein-Barr virus mononucleosis can frequently present with mild elevation of transaminases, but very rarely can have marked elevation of bilirubin, which may make clinicians doubt that the infection is the sole culprit of the process.

Indexed as

cholestasisEBVhepatitisInfectious mononucleosis

Identifiers

PMID38023960
PMCPMC10659742
OpenAlexW4388816687

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.