Evidence map›Paper›PMID 38023802›Full record

ArticleJournal of dental research, dental clinics, dental prospects2023

The association between oral inflammatory load and semen and sperm functional analysis: A cross-sectional study.

Reza Pourabbas, Samin Farajzadeh, Amirreza Babaloo, Azar Pazhohan, Mehrnoosh Sadighi, Sakineh Hajebrahimi, Sajjad Pourabbas, Howard C Tenenbaum

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In one paragraph

Article in Journal of dental research, dental clinics, dental prospects, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Reza PourabbasDepartment of Periodontology, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.ORCID https://orcid.org/0000-0002-8860-4006
Samin FarajzadehDepartment of Periodontology, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.ORCID https://orcid.org/0000-0001-9818-2495
Amirreza BabalooDepartment of Periodontology, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.
Azar PazhohanOmid Infertility Treatment Center, Valiasr Hospital, Tabriz, Iran.
Mehrnoosh SadighiDepartment of Periodontology, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.
Sakineh HajebrahimiResearch Center for Evidence-based Medicine, Urology Department, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Sajjad PourabbasSchool of Kinesiology and Health Sciences, York University, Toronto, Canada.
Howard C TenenbaumFaculty of Dentistry, University of Toronto, Toronto, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Studies have suggested a correlation between periodontitis and reduced male fertility. Inflammation has been described as the link between these ailments. Oral inflammatory load (OIL) can be measured through oral polymorphonuclear neutrophil (oPMN) count, which is associated with periodontal diseases. This cross-sectional study assessed the possible correlation between OIL and the functional parameters of sperm cells. Methods: In 229 volunteers, oral rinse and semen samples were assessed for oPMN, semen polymorphonuclears (sPMNs), sperm concentration, total sperm count, motility, morphology, and sperm DNA fragmentation index (SDFi). A multiple linear regression model was conducted to evaluate the relationships between oPMN and semen parameters. Results: The effect of elevated oPMN counts on total motility rate, progressive rate, and percentage of sperm cells with normal morphology was significant ( Conclusion: OIL, as represented by oPMN counts, might affect male fertility as there is a positive correlation between the levels of these inflammatory cells and decreased sperm motility, abnormal morphological changes, increased sPMN counts, and increased SDFi.

Indexed as

InfertilityInflammationMaleNeutrophilsPeriodontitisSpermatozoa

Identifiers

PMID38023802
PMCPMC10676540

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.