Evidence map›Paper›PMID 38023615›Full record

ArticleJournal of immunology research2023

Sestrin2 Regulates Endoplasmic Reticulum Stress-Dependent Ferroptosis to Engage Pulmonary Fibrosis by Nuclear Factor Erythroid 2-Related Factor 2/Activating Transcription Factor 4 (NRF2/ATF4).

Zhaoxing Dong, Ting Li, Cenli Wang, Yong Zhou, Zhongkai Tong, Xuekui Du

Open access · goldAbstract read
In one paragraph

Article in Journal of immunology research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Zhaoxing DongDepartment of Respiratory and Critical Care Medicine, Ningbo No. 2 Hospital, Ningbo 315000, Zhejiang Province, China.ORCID https://orcid.org/0000-0002-3071-0711
Ting LiDepartment of Respiratory and Critical Care Medicine, Ningbo No. 2 Hospital, Ningbo 315000, Zhejiang Province, China.
Cenli WangDepartment of Respiratory and Critical Care Medicine, Xiangshan Red Cross Taiwan Compatriot Hospital Medical and Health Group, Ningbo 315000, Zhejiang, China.
Yong ZhouDepartment of Respiratory and Critical Care Medicine, Ningbo No. 2 Hospital, Ningbo 315000, Zhejiang Province, China.
Zhongkai TongDepartment of Respiratory and Critical Care Medicine, Ningbo No. 2 Hospital, Ningbo 315000, Zhejiang Province, China.
Xuekui DuDepartment of Respiratory and Critical Care Medicine, Ningbo No. 2 Hospital, Ningbo 315000, Zhejiang Province, China.ORCID https://orcid.org/0009-0008-5700-0980
Ningbo No. 2 Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulmonary fibrosis (PF) can lead to chronic inflammation, the destruction of alveoli and irreversible lung damage. Sestrin2 is a highly protective stress-inducible protein that is involved in the cell response to various stress factors and the regulation of homeostasis and has a certain protective effect against PF. In this study, TGF-

Indexed as

FerroptosisPulmonary FibrosisActivating Transcription Factor 4AnimalsEndoplasmic Reticulum StressInflammationMiceNF-E2-Related Factor 2Activating Transcription Factor 4NF-E2-Related Factor 2

Identifiers

PMID38023615
PMCPMC10645490
OpenAlexW4388451913

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.