ArticleHorticulture research2023
Telomere-to-telomere assembly of cassava genome reveals the evolution of cassava and divergence of allelic expression.
Article in Horticulture research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 26 citations in OpenAlex.
- Establishment of a Near-Infrared Spectroscopy-Based Screening Framework for Key Quality Indicators of Cassava Varieties.Foods (Basel, Switzerland) · 2026Article
- CassavaMDB: an integrated multi-omics database for functional genomics and molecular breeding in cassava.Science China. Life sciences · 2026Article
- CassavaDB: An integrated multi-omics resource for functional genomics and molecular breeding of cassava.Innovation (Cambridge (Mass.)) · 2026Review
- Pan-Genome Analysis and Expression Profiling ofGenes · 2026Article
- Advances and prospects of genomic-assisted breeding in roots, tubers, and banana crops.Frontiers in plant science · 2026Review
- Genome-Wide Identification and Expression Analysis ofPlants (Basel, Switzerland) · 2025Article
- TeloComp: An efficient toolkit for accurate assembly of the telomeres in T2T genomes.Plant communications · 2025Article
- RAGA: a reference-assisted genome assembly tool for efficient population-scale assembly.Horticulture research · 2025Article
- Analysis of telomere-to-telomere genome of red carrot TXH4 elucidates the role of DcLCYE and DcLCYB1 in lycopene accumulation in carrot.Horticulture research · 2025Article
- Hybridization Drives Trait Integration in Telomere-To-Telomere Apocynum Genomes.Plant biotechnology journal · 2025Article
- The haplotype-resolved assembly of COL40 a cassava (Manihot esculenta) line with broad-spectrum resistance against viruses causing Cassava brown streak disease unveils a region of highly repeated elements on chromosome 12.G3 (Bethesda, Md.) · 2025Article
- Telomere-to-telomere gap-free genome assembly provides genetic insight into the triterpenoid saponins biosynthesis inHorticulture research · 2025Article
- Advancements and strategies of genetic improvement in cassava (Horticulture research · 2025Article
- TropiCODB: A multi-omics resource for supporting biodesign in tropical crops.Biodesign research · 2025Article
- The role of pangenomics in orphan crop improvement.Nature communications · 2025Review
- The gap-free genome ofHorticulture research · 2024Article
- Haplotype-resolved T2T reference genomes for wild and domesticated accessions shed new insights into the domestication of jujube.Horticulture research · 2024Article
Corrections and comments
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Authors and funding
18 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cassava is a crucial crop that makes a significant contribution to ensuring human food security. However, high-quality telomere-to-telomere cassava genomes have not been available up to now, which has restricted the progress of haploid molecular breeding for cassava. In this study, we constructed two nearly complete haploid resolved genomes and an integrated, telomere-to-telomere gap-free reference genome of an excellent cassava variety, 'Xinxuan 048', thereby providing a new high-quality genomic resource. Furthermore, the evolutionary history of several species within the Euphorbiaceae family was revealed. Through comparative analysis of haploid genomes, it was found that two haploid genomes had extensive differences in linear structure, transcriptome features, and epigenetic characteristics. Genes located within the highly divergent regions and differentially expressed alleles are enriched in the functions of auxin response and the starch synthesis pathway. The high heterozygosity of cassava 'Xinxuan 048' leads to rapid trait segregation in the first selfed generation. This study provides a theoretical basis and genomic resource for molecular breeding of cassava haploids.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.