Evidence map›Paper›PMID 38023413›Full record

ArticleInfection and drug resistance2023

Within-Host Resistance and Virulence Evolution of a Hypervirulent Carbapenem-Resistant

Cong Zhou, Hui Zhang, Maosuo Xu, Yajuan Liu, Baoyu Yuan, Yong Lin, Fang Shen

Open access · goldAbstract read
In one paragraph

Article in Infection and drug resistance, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Comparative Proteomic Profiling of ClinicalJournal of extracellular biology · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Concurrent classical and hypervirulentFrontiers in cellular and infection microbiology · 2025
    Article
  10. Review
  11. Article
  12. Article
  13. TiOMicroorganisms · 2024
    Review
  14. Multidrug-resistant ST11-KL64 hypervirulentFrontiers in pediatrics · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Cong ZhouDepartment of Clinical Laboratory, Shanghai Fifth People's Hospital, Fudan University, Shanghai, People's Republic of China.ORCID 0000-0003-0818-3801
Hui ZhangDepartment of Clinical Laboratory, Shanghai Fifth People's Hospital, Fudan University, Shanghai, People's Republic of China.
Maosuo XuDepartment of Clinical Laboratory, Shanghai Fifth People's Hospital, Fudan University, Shanghai, People's Republic of China.
Yajuan LiuDepartment of Clinical Laboratory, Shanghai Fifth People's Hospital, Fudan University, Shanghai, People's Republic of China.
Baoyu YuanDepartment of Clinical Laboratory, Shanghai Children's Hospital, Shanghai Jiao Tong University, Shanghai, People's Republic of China.
Yong LinDepartment of Clinical Laboratory, Shanghai Fifth People's Hospital, Fudan University, Shanghai, People's Republic of China.
Fang ShenDepartment of Clinical Laboratory, Shanghai Fifth People's Hospital, Fudan University, Shanghai, People's Republic of China.
Fudan University · CNShanghai Jiao Tong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Hypervirulent carbapenem-resistant Methods: The bacterial identification, antimicrobial susceptibility, hypermucoviscosity, virulence factors, MLST and serotypes were profiled.The clonal homology and plasmid acquisition among hv-CRKP strains were detected by XbaI and S1-PFGE. The virulence potential of the strains was evaluated using Results: Four Conclusion: This study shows that ST11-KL64 hv-CRKP can further evolve to acquire aminoglycoside resistance accompanied by decreased virulence to adapt to antibiotic pressure in the host.

Indexed as

hypervirulent carbapenem-resistant Klebsiella pneumoniaeplasmidswhole-genome sequencingwithin-host evolution

Identifiers

PMID38023413
PMCPMC10658960
OpenAlexW4388735637

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.