Evidence map›Paper›PMID 38023401›Full record

ArticleInfection and drug resistance2023

Molecular Epidemiology of Carbapenem Resistant

Wanni Cai, Jianbang Kang, Yanbin Ma, Donghong Yin, Yan Song, Yujie Liu, Jinju Duan

Open access · goldAbstract read
In one paragraph

Article in Infection and drug resistance, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
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  5. Article
  6. Epidemiological and characteristic differences of hypervirulent and classicalFrontiers in cellular and infection microbiology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Wanni Cai *School of Pharmacy, Shanxi Medical University, Taiyuan, 030001, People's Republic of China.
Jianbang Kang *Department of Microbiology, Second Hospital of Shanxi Medical University, Taiyuan, 030001, People's Republic of China.
Yanbin MaSchool of Pharmacy, Shanxi Medical University, Taiyuan, 030001, People's Republic of China.ORCID 0000-0003-1320-1250
Donghong YinDepartment of Pharmacy, Second Hospital of Shanxi Medical University, Taiyuan, 030001, People's Republic of China.
Yan SongDepartment of Pharmacy, Second Hospital of Shanxi Medical University, Taiyuan, 030001, People's Republic of China.
Yujie LiuSchool of Pharmacy, Shanxi Medical University, Taiyuan, 030001, People's Republic of China.
Jinju DuanDepartment of Pharmacy, Second Hospital of Shanxi Medical University, Taiyuan, 030001, People's Republic of China.ORCID 0000-0001-6175-5923
Shanxi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: In this article, we studied in detail 74 Carbapenem Resistant Patients and Methods: From 2018 to 2021, we collected 74 clinical CRKP from 11 hospitals in Shanxi Province. Clinical data were obtained from medical records, and all isolates were subjected to antimicrobial susceptibility testing, multi locus sequence typing, capsular serotypes, resistant gene profiles and virulence gene profiles. The synergistic activity was performed by microdilution checkerboard method. Results: Our study found differences in the clinical characteristics of CRKP between regions in Shanxi. Sequence type (ST) 11 was the dominant ST in Shanxi; however, the ST types in Shanxi had become more diverse over time and the proportion of STs showed a more balanced distribution with a significant decrease in ST11. NDM was the most common carbapenemase in Shanxi. In addition, the STs, carbapenemases, serotypes and virulence gene distribution varied by region in Shanxi. Moreover, tigecycline in combination with carbapenems and aztreonam had an excellent synergistic effect on CRKP in vitro. Conclusion: The results of this study provide essential insight into development of effective strategies for control of CRKP in Shanxi.

Indexed as

antimicrobial resistancecarbapenemaseChinaKlebsiella pneumoniaesynergistic effectvirulence

Identifiers

PMID38023401
PMCPMC10676093
OpenAlexW4388832373

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.